PI 3 Kinase Related Kinases-Independent Proteolysis of BRCA1 Regulates Rad51 Recruitment during Genotoxic Stress in Human Cells

Ian Hammond-Martel; Helen Pak; Helen Yu; Raphael Rouget; Andrew A. Horwitz; Jeffrey D. Parvin; Elliot A. Drobetsky; El Bachir Affar

doi:10.1371/journal.pone.0014027

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Peer-reviewed

Research Article

PI 3 Kinase Related Kinases-Independent Proteolysis of BRCA1 Regulates Rad51 Recruitment during Genotoxic Stress in Human Cells

Ian Hammond-Martel,

Affiliation Department of Medicine, Maisonneuve-Rosemont Hospital Research Center, University of Montréal, Montréal, Québec, Canada
⨯
Helen Pak,

Affiliation Department of Medicine, Maisonneuve-Rosemont Hospital Research Center, University of Montréal, Montréal, Québec, Canada
⨯
Helen Yu,

Affiliation Department of Medicine, Maisonneuve-Rosemont Hospital Research Center, University of Montréal, Montréal, Québec, Canada
⨯
Raphael Rouget,

Affiliation Department of Medicine, Maisonneuve-Rosemont Hospital Research Center, University of Montréal, Montréal, Québec, Canada
⨯
Andrew A. Horwitz,

Current address: University of California San Francisco, San Francisco, California, United States of America

Affiliation Department of Pathology, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, United States of America
⨯
Jeffrey D. Parvin,

Current address: The Ohio State University Department of Biomedical Informatics, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America

Affiliation Department of Pathology, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, United States of America
⨯
Elliot A. Drobetsky,

Affiliation Department of Medicine, Maisonneuve-Rosemont Hospital Research Center, University of Montréal, Montréal, Québec, Canada
⨯
El Bachir Affar

* E-mail: aelbachir.hmr@ssss.gouv.qc.ca

Affiliation Department of Medicine, Maisonneuve-Rosemont Hospital Research Center, University of Montréal, Montréal, Québec, Canada
⨯

PI 3 Kinase Related Kinases-Independent Proteolysis of BRCA1 Regulates Rad51 Recruitment during Genotoxic Stress in Human Cells

Ian Hammond-Martel,
Helen Pak,
Helen Yu,
Raphael Rouget,
Andrew A. Horwitz,
Jeffrey D. Parvin,
Elliot A. Drobetsky,
El Bachir Affar

Published: November 17, 2010
https://doi.org/10.1371/journal.pone.0014027

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