Perilipin Overexpression in White Adipose Tissue Induces a Brown Fat-Like Phenotype

Takashi Sawada; Hideaki Miyoshi; Kohei Shimada; Akira Suzuki; Yuko Okamatsu-Ogura; James W. Perfield II; Takuma Kondo; So Nagai; Chikara Shimizu; Narihito Yoshioka; Andrew S. Greenberg; Kazuhiro Kimura; Takao Koike

doi:10.1371/journal.pone.0014006

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Open Access

Peer-reviewed

Research Article

Perilipin Overexpression in White Adipose Tissue Induces a Brown Fat-Like Phenotype

Takashi Sawada,

Affiliation Department of Internal Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯
Hideaki Miyoshi ,

* E-mail: hmiyoshi@med.hokudai.ac.jp

Affiliation Department of Internal Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯
Kohei Shimada,

Affiliation Department of Biomedical Sciences, Hokkaido University Graduate School of Veterinary Medicine, Sapporo, Japan
⨯
Akira Suzuki,

Affiliation Department of Pathology, KKR Sapporo Medical Center, Sapporo, Japan
⨯
Yuko Okamatsu-Ogura,

Affiliation Department of Biomedical Sciences, Hokkaido University Graduate School of Veterinary Medicine, Sapporo, Japan
⨯
James W. Perfield II,

Affiliation Department of Nutrition and Exercise Physiology and Food Science, University of Missouri, Columbia, Missouri, United States of America
⨯
Takuma Kondo,

Affiliation Department of Internal Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯
So Nagai,

Affiliation Department of Internal Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯
Chikara Shimizu,

Affiliation Department of Internal Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯
Narihito Yoshioka,

Affiliation Department of Internal Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯
Andrew S. Greenberg,

Affiliation Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, United States of America
⨯
Kazuhiro Kimura,

Affiliation Department of Biomedical Sciences, Hokkaido University Graduate School of Veterinary Medicine, Sapporo, Japan
⨯
Takao Koike

Affiliation Department of Internal Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan
⨯

Perilipin Overexpression in White Adipose Tissue Induces a Brown Fat-Like Phenotype

Takashi Sawada,
Hideaki Miyoshi,
Kohei Shimada,
Akira Suzuki,
Yuko Okamatsu-Ogura,
James W. Perfield II,
Takuma Kondo,
So Nagai,
Chikara Shimizu,
Narihito Yoshioka

Published: November 16, 2010
https://doi.org/10.1371/journal.pone.0014006

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18 Nov 2010
07:03 GMT
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Publisher's Note: minor correction Posted by stakashi on 18 Nov 2010 at 07:03 GMT

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Adipocytes
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Lipids
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Adipose tissue
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Gene expression
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Fatty acids
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