Reactive Oxygen Species Are Required for Maintenance and Differentiation of Primary Lung Fibroblasts in Idiopathic Pulmonary Fibrosis

Marialuisa Bocchino; Savina Agnese; Evelina Fagone; Silvia Svegliati; Domenico Grieco; Carlo Vancheri; Armando Gabrielli; Alessandro Sanduzzi; Enrico V. Avvedimento

doi:10.1371/journal.pone.0014003

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Peer-reviewed

Research Article

Reactive Oxygen Species Are Required for Maintenance and Differentiation of Primary Lung Fibroblasts in Idiopathic Pulmonary Fibrosis

Marialuisa Bocchino ,

Contributed equally to this work with: Marialuisa Bocchino, Savina Agnese

* E-mail: marialuisa.bocchino@unina.it

Affiliations Dipartimento di Medicina Clinica e Sperimentale, Sezione di Malattie dell'Apparato Respiratorio, Università Federico II, Napoli, Italy, Dipartimento di Biologia e Patologia Cellulare e Molecolare “L. Califano”, Università Federico II, Napoli, Italy
⨯
Savina Agnese ,

Contributed equally to this work with: Marialuisa Bocchino, Savina Agnese

Affiliation Dipartimento di Biologia e Patologia Cellulare e Molecolare “L. Califano”, Università Federico II, Napoli, Italy
⨯
Evelina Fagone,

Affiliation Dipartimento di Medicina Interna e Specialistica, Sezione di Malattie Respiratorie, Università di Catania, Catania, Italy
⨯
Silvia Svegliati,

Affiliation Dipartimento di Scienze Mediche e Chirurgiche, Sezione di Clinica Medica, Università Politecnica delle Marche, Ancona, Italy
⨯
Domenico Grieco,

Affiliation Dipartimento di Biologia e Patologia Cellulare e Molecolare “L. Califano”, Università Federico II, Napoli, Italy
⨯
Carlo Vancheri,

Affiliation Dipartimento di Medicina Interna e Specialistica, Sezione di Malattie Respiratorie, Università di Catania, Catania, Italy
⨯
Armando Gabrielli,

Affiliation Dipartimento di Scienze Mediche e Chirurgiche, Sezione di Clinica Medica, Università Politecnica delle Marche, Ancona, Italy
⨯
Alessandro Sanduzzi,

Affiliation Dipartimento di Medicina Clinica e Sperimentale, Sezione di Malattie dell'Apparato Respiratorio, Università Federico II, Napoli, Italy
⨯
Enrico V. Avvedimento

Affiliation Dipartimento di Biologia e Patologia Cellulare e Molecolare “L. Califano”, Università Federico II, Napoli, Italy
⨯

Reactive Oxygen Species Are Required for Maintenance and Differentiation of Primary Lung Fibroblasts in Idiopathic Pulmonary Fibrosis

Marialuisa Bocchino,
Savina Agnese,
Evelina Fagone,
Silvia Svegliati,
Domenico Grieco,
Carlo Vancheri,
Armando Gabrielli,
Alessandro Sanduzzi,
Enrico V. Avvedimento

Published: November 16, 2010
https://doi.org/10.1371/journal.pone.0014003

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Tyrosine kinases
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