In Silico Ascription of Gene Expression Differences to Tumor and Stromal Cells in a Model to Study Impact on Breast Cancer Outcome

Simen Myhre; Hayat Mohammed; Trine Tramm; Jan Alsner; Greg Finak; Morag Park; Jens Overgaard; Anne-Lise Børresen-Dale; Arnoldo Frigessi; Therese Sørlie

doi:10.1371/journal.pone.0014002

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Open Access

Peer-reviewed

Research Article

In Silico Ascription of Gene Expression Differences to Tumor and Stromal Cells in a Model to Study Impact on Breast Cancer Outcome

Simen Myhre ,

Contributed equally to this work with: Simen Myhre, Hayat Mohammed

* E-mail: simenmy@rr-research.no

Affiliations Department of Genetics, Institute for Cancer Research, Division of Surgery and Cancer, Oslo University Hospital Radiumhospitalet, Oslo, Norway, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
⨯
Hayat Mohammed ,

Contributed equally to this work with: Simen Myhre, Hayat Mohammed

Affiliations Department of Genetics, Institute for Cancer Research, Division of Surgery and Cancer, Oslo University Hospital Radiumhospitalet, Oslo, Norway, Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
⨯
Trine Tramm,

Affiliation Department of Oncology, Aarhus University Hospital, Aarhus, Denmark
⨯
Jan Alsner,

Affiliation Department of Oncology, Aarhus University Hospital, Aarhus, Denmark
⨯
Greg Finak,

Affiliation Rosalind and Morris Goodman Cancer Centre, McGill University, Montreal, Canada
⨯
Morag Park,

Affiliation Rosalind and Morris Goodman Cancer Centre, McGill University, Montreal, Canada
⨯
Jens Overgaard,

Affiliation Department of Oncology, Aarhus University Hospital, Aarhus, Denmark
⨯
Anne-Lise Børresen-Dale,

Affiliations Department of Genetics, Institute for Cancer Research, Division of Surgery and Cancer, Oslo University Hospital Radiumhospitalet, Oslo, Norway, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
⨯
Arnoldo Frigessi,

Affiliation Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
⨯
Therese Sørlie

Affiliations Department of Genetics, Institute for Cancer Research, Division of Surgery and Cancer, Oslo University Hospital Radiumhospitalet, Oslo, Norway, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
⨯

In Silico Ascription of Gene Expression Differences to Tumor and Stromal Cells in a Model to Study Impact on Breast Cancer Outcome

Simen Myhre,
Hayat Mohammed,
Trine Tramm,
Jan Alsner,
Greg Finak,
Morag Park,
Jens Overgaard,
Anne-Lise Børresen-Dale,
Arnoldo Frigessi,
Therese Sørlie

Published: November 19, 2010
https://doi.org/10.1371/journal.pone.0014002

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Breast cancer
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Cancers and neoplasms
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Gene expression
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Adipocytes
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