Phenotypic Complexity, Measurement Bias, and Poor Phenotypic Resolution Contribute to the Missing Heritability Problem in Genetic Association Studies

• Sophie van der Sluis ,

  * E-mail: sophie.van.der.sluis@cncr.vu.nl

  Affiliations Functional Genomics Section, Department of Clinical Genetics, Center for Neurogenomics and Cognitive Research (CNCR), VU University and VU University Medical Center, Amsterdam, The Netherlands, Functional Genomics Section, Center for Neurogenomics and Cognitive Research (CNCR), VU University, Amsterdam, The Netherlands

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• Matthijs Verhage,

  Affiliation Functional Genomics Section, Department of Clinical Genetics, Center for Neurogenomics and Cognitive Research (CNCR), VU University and VU University Medical Center, Amsterdam, The Netherlands

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• Danielle Posthuma,

  Affiliations Functional Genomics Section, Department of Clinical Genetics, Center for Neurogenomics and Cognitive Research (CNCR), VU University and VU University Medical Center, Amsterdam, The Netherlands, Medical Genomics Section, Department of Clinical Genetics, Center for Neurogenomics and Cognitive Research (CNCR), VU University and VU University Medical Center, Amsterdam, The Netherlands

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• Conor V. Dolan

  Affiliation Department of Psychology, Faculty of Social and Behavioural Sciences (FMG), University of Amsterdam, Amsterdam, The Netherlands

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