Flavopiridol Pharmacogenetics: Clinical and Functional Evidence for the Role of SLCO1B1/OATP1B1 in Flavopiridol Disposition

• Wenjun Ni,

  Affiliation Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America

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• Jia Ji,

  Affiliation Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America

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• Zunyan Dai,

  Affiliation Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Audrey Papp,

  Affiliation Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Amy J. Johnson,

  Affiliation Division of Hematology and Oncology, The Ohio State University, Columbus, Ohio, United States of America

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• Sunjoo Ahn,

  Affiliation Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America

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• Katherine L. Farley,

  Affiliation Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America

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• Thomas S. Lin,

  Affiliations Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America, Division of Hematology and Oncology, The Ohio State University, Columbus, Ohio, United States of America

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• James T. Dalton,

  Affiliations Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America, Division of Hematology and Oncology, The Ohio State University, Columbus, Ohio, United States of America

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• Xiaobai Li,

  Affiliation Division of Biostatistics, College of Public Health, The Ohio State University, Columbus, Ohio, United States of America

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• David Jarjoura,

  Affiliation Division of Biostatistics, College of Public Health, The Ohio State University, Columbus, Ohio, United States of America

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• John C. Byrd,

  Affiliations Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America, Division of Hematology and Oncology, The Ohio State University, Columbus, Ohio, United States of America

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• Wolfgang Sadee,

  Affiliations Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America, Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Michael R. Grever,

  Affiliations Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America, Division of Hematology and Oncology, The Ohio State University, Columbus, Ohio, United States of America

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• Mitch A. Phelps

  * E-mail: mitch.phelps@osumc.edu

  Affiliations Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America, Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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