Study of the Molecular Recognition of Aptamers Selected through Ovarian Cancer Cell-SELEX

Dimitri Van Simaeys; Dalia López-Colón; Kwame Sefah; Rebecca Sutphen; Elizabeth Jimenez; Weihong Tan

doi:10.1371/journal.pone.0013770

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Peer-reviewed

Research Article

Study of the Molecular Recognition of Aptamers Selected through Ovarian Cancer Cell-SELEX

Dimitri Van Simaeys ,

Contributed equally to this work with: Dimitri Van Simaeys, Dalia López-Colón

Affiliations Department of Chemistry, Center for Research at Bio/Nano Interface, University of Florida, Gainesville, Florida, United States of America, Shands Cancer and Genetic Research Center, Department of Physiology and Functional Genomics, University of Florida, Gainesville, Florida, United States of America
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Dalia López-Colón ,

Contributed equally to this work with: Dimitri Van Simaeys, Dalia López-Colón

Affiliations Department of Chemistry, Center for Research at Bio/Nano Interface, University of Florida, Gainesville, Florida, United States of America, Shands Cancer and Genetic Research Center, Department of Physiology and Functional Genomics, University of Florida, Gainesville, Florida, United States of America
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Kwame Sefah,

Affiliations Department of Chemistry, Center for Research at Bio/Nano Interface, University of Florida, Gainesville, Florida, United States of America, Shands Cancer and Genetic Research Center, Department of Physiology and Functional Genomics, University of Florida, Gainesville, Florida, United States of America
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Rebecca Sutphen,

Affiliation Department of Pediatrics, College of Medicine, University of South Florida, Tampa, Florida, United States of America
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Elizabeth Jimenez,

Affiliations Department of Chemistry, Center for Research at Bio/Nano Interface, University of Florida, Gainesville, Florida, United States of America, Shands Cancer and Genetic Research Center, Department of Physiology and Functional Genomics, University of Florida, Gainesville, Florida, United States of America
⨯
Weihong Tan

* E-mail: tan@chem.ufl.edu

Affiliations Department of Chemistry, Center for Research at Bio/Nano Interface, University of Florida, Gainesville, Florida, United States of America, Shands Cancer and Genetic Research Center, Department of Physiology and Functional Genomics, University of Florida, Gainesville, Florida, United States of America, Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America
⨯

Study of the Molecular Recognition of Aptamers Selected through Ovarian Cancer Cell-SELEX

Dimitri Van Simaeys,
Dalia López-Colón,
Kwame Sefah,
Rebecca Sutphen,
Elizabeth Jimenez,
Weihong Tan

Published: November 1, 2010
https://doi.org/10.1371/journal.pone.0013770

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Ovarian cancer
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Cell binding
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Cell binding assay
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Proteases
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Binding analysis
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