Point Mutations in c-Myc Uncouple Neoplastic Transformation from Multiple Other Phenotypes in Rat Fibroblasts

J. Anthony Graves; Kristi Rothermund; Tao Wang; Wei Qian; Bennett Van Houten; Edward V. Prochownik

doi:10.1371/journal.pone.0013717

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Peer-reviewed

Research Article

Point Mutations in c-Myc Uncouple Neoplastic Transformation from Multiple Other Phenotypes in Rat Fibroblasts

J. Anthony Graves ,

* E-mail: gravja@chp.edu

Affiliation Division of Hematology/Oncology, Department of Pediatrics, Children's Hospital of Pittsburgh of The University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
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Kristi Rothermund,

Affiliation Division of Hematology/Oncology, Department of Pediatrics, Children's Hospital of Pittsburgh of The University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
⨯
Tao Wang,

Affiliations The University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America, The Department of Pharmacology and Chemical Biology, The University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
⨯
Wei Qian,

Affiliations The University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America, The Department of Pharmacology and Chemical Biology, The University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
⨯
Bennett Van Houten,

Affiliations The University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America, The Department of Pharmacology and Chemical Biology, The University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
⨯
Edward V. Prochownik

Affiliations Division of Hematology/Oncology, Department of Pediatrics, Children's Hospital of Pittsburgh of The University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America, The University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America, The Department of Microbiology and Molecular Genetics, The University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
⨯

Point Mutations in c-Myc Uncouple Neoplastic Transformation from Multiple Other Phenotypes in Rat Fibroblasts

J. Anthony Graves,
Kristi Rothermund,
Tao Wang,
Wei Qian,
Bennett Van Houten,
Edward V. Prochownik

Published: October 28, 2010
https://doi.org/10.1371/journal.pone.0013717

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