Gene Network Analysis of Bone Marrow Mononuclear Cells Reveals Activation of Multiple Kinase Pathways in Human Systemic Lupus Erythematosus

Magdalene Nakou; George Bertsias; Ilias Stagakis; Michael Centola; Ioannis Tassiulas; Maria Hatziapostolou; Iraklis Kritikos; George Goulielmos; Dimitrios T. Boumpas; Dimitrios Iliopoulos

doi:10.1371/journal.pone.0013351

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Peer-reviewed

Research Article

Gene Network Analysis of Bone Marrow Mononuclear Cells Reveals Activation of Multiple Kinase Pathways in Human Systemic Lupus Erythematosus

Magdalene Nakou ,

Contributed equally to this work with: Magdalene Nakou, George Bertsias, Dimitrios T. Boumpas, Dimitrios Iliopoulos

Affiliation Division of Rheumatology, Clinical Immunology and Allergy, University of Crete Medical School, Heraklion, Greece
⨯
George Bertsias ,

Contributed equally to this work with: Magdalene Nakou, George Bertsias, Dimitrios T. Boumpas, Dimitrios Iliopoulos

Affiliations Division of Rheumatology, Clinical Immunology and Allergy, University of Crete Medical School, Heraklion, Greece, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Greece
⨯
Ilias Stagakis,

Affiliations Division of Rheumatology, Clinical Immunology and Allergy, University of Crete Medical School, Heraklion, Greece, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Greece
⨯
Michael Centola,

Affiliation Microarray Research Facility, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America
⨯
Ioannis Tassiulas,

Affiliations Division of Rheumatology, Clinical Immunology and Allergy, University of Crete Medical School, Heraklion, Greece, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Greece
⨯
Maria Hatziapostolou,

Affiliations Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Iraklis Kritikos †,

† Deceased.

Affiliation Division of Rheumatology, Clinical Immunology and Allergy, University of Crete Medical School, Heraklion, Greece
⨯
George Goulielmos,

Affiliation Division of Rheumatology, Clinical Immunology and Allergy, University of Crete Medical School, Heraklion, Greece
⨯
Dimitrios T. Boumpas ,

Contributed equally to this work with: Magdalene Nakou, George Bertsias, Dimitrios T. Boumpas, Dimitrios Iliopoulos

Affiliations Division of Rheumatology, Clinical Immunology and Allergy, University of Crete Medical School, Heraklion, Greece, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Greece
⨯
Dimitrios Iliopoulos

Contributed equally to this work with: Magdalene Nakou, George Bertsias, Dimitrios T. Boumpas, Dimitrios Iliopoulos

* E-mail: dimitrios_iliopoulos@dfci.harvard.edu

Affiliations Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Gene Network Analysis of Bone Marrow Mononuclear Cells Reveals Activation of Multiple Kinase Pathways in Human Systemic Lupus Erythematosus

Magdalene Nakou,
George Bertsias,
Ilias Stagakis,
Michael Centola,
Ioannis Tassiulas,
Maria Hatziapostolou,
Iraklis Kritikos,
George Goulielmos,
Dimitrios T. Boumpas,
Dimitrios Iliopoulos

Published: October 14, 2010
https://doi.org/10.1371/journal.pone.0013351

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