Anthrax Lethal Toxin Suppresses Murine Cardiomyocyte Contractile Function and Intracellular Ca2+ Handling via a NADPH Oxidase-Dependent Mechanism

Open Access

Peer-reviewed

Research Article

Anthrax Lethal Toxin Suppresses Murine Cardiomyocyte Contractile Function and Intracellular Ca²⁺ Handling via a NADPH Oxidase-Dependent Mechanism

Machender R. Kandadi,

Affiliation Center for Cardiovascular Research and Alternative Medicine, University of Wyoming College of Health Sciences, Laramie, Wyoming, United States of America
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Yinan Hua,

Affiliation Center for Cardiovascular Research and Alternative Medicine, University of Wyoming College of Health Sciences, Laramie, Wyoming, United States of America
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Heng Ma,

Affiliation Center for Cardiovascular Research and Alternative Medicine, University of Wyoming College of Health Sciences, Laramie, Wyoming, United States of America
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Qun Li,

Affiliation Center for Cardiovascular Research and Alternative Medicine, University of Wyoming College of Health Sciences, Laramie, Wyoming, United States of America
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Shu-ru Kuo,

Affiliation Cancer Research Institute of Scott and White Memorial Hospital, Temple, Texas, United States of America
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Arthur E. Frankel,

Affiliation Cancer Research Institute of Scott and White Memorial Hospital, Temple, Texas, United States of America
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Jun Ren

* E-mail: jren@uwyo.edu

Affiliation Center for Cardiovascular Research and Alternative Medicine, University of Wyoming College of Health Sciences, Laramie, Wyoming, United States of America
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Toxins
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Cardiomyocytes
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Anthrax
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Bacterial lethality
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Superoxides
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Cell signaling
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Autophagic cell death
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Heart
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