Gene Expression Signature-Based Screening Identifies New Broadly Effective Influenza A Antivirals

Laurence Josset; Julien Textoris; Béatrice Loriod; Olivier Ferraris; Vincent Moules; Bruno Lina; Catherine N'Guyen; Jean-Jacques Diaz; Manuel Rosa-Calatrava

doi:10.1371/journal.pone.0013169

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Peer-reviewed

Research Article

Gene Expression Signature-Based Screening Identifies New Broadly Effective Influenza A Antivirals

Laurence Josset ,

* E-mail: laurence.josset@chu-lyon.fr (LJ); manuel.rosa-calatrava@univ-lyon1.fr (MRC)

Affiliations Centre National de la Recherche Scientifique (CNRS) FRE 3011 Virologie et Pathologie Humaine, Université Lyon 1, Lyon, France, Laboratoire de Virologie Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, Lyon, France
⨯
Julien Textoris,

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM) U928 Technologies Avancées pour le Génome et la Clinique, Université de la Méditerranée, Marseille, France, Centre National de la Recherche Scientifique (CNRS) UMR 5534, Centre Léon Bérard, Centre de Génétique Moléculaire et Cellulaire, Université Lyon 1, Lyon, France, Service d'anesthésie et de réanimation Hôpital Nord, Assistance Publique - Hôpitaux de Marseille, Marseille, France
⨯
Béatrice Loriod,

Affiliation Institut National de la Santé et de la Recherche Médicale (INSERM) U928 Technologies Avancées pour le Génome et la Clinique, Université de la Méditerranée, Marseille, France
⨯
Olivier Ferraris,

Affiliation Centre National de la Recherche Scientifique (CNRS) FRE 3011 Virologie et Pathologie Humaine, Université Lyon 1, Lyon, France
⨯
Vincent Moules,

Affiliation Centre National de la Recherche Scientifique (CNRS) FRE 3011 Virologie et Pathologie Humaine, Université Lyon 1, Lyon, France
⨯
Bruno Lina,

Affiliations Centre National de la Recherche Scientifique (CNRS) FRE 3011 Virologie et Pathologie Humaine, Université Lyon 1, Lyon, France, Laboratoire de Virologie Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, Lyon, France
⨯
Catherine N'Guyen,

Affiliation Institut National de la Santé et de la Recherche Médicale (INSERM) U928 Technologies Avancées pour le Génome et la Clinique, Université de la Méditerranée, Marseille, France
⨯
Jean-Jacques Diaz,

Affiliation Centre National de la Recherche Scientifique (CNRS) UMR 5534, Centre Léon Bérard, Centre de Génétique Moléculaire et Cellulaire, Université Lyon 1, Lyon, France
⨯
Manuel Rosa-Calatrava

* E-mail: laurence.josset@chu-lyon.fr (LJ); manuel.rosa-calatrava@univ-lyon1.fr (MRC)

Affiliation Centre National de la Recherche Scientifique (CNRS) FRE 3011 Virologie et Pathologie Humaine, Université Lyon 1, Lyon, France
⨯

Gene Expression Signature-Based Screening Identifies New Broadly Effective Influenza A Antivirals

Laurence Josset,
Julien Textoris,
Béatrice Loriod,
Olivier Ferraris,
Vincent Moules,
Bruno Lina,
Catherine N'Guyen,
Jean-Jacques Diaz,
Manuel Rosa-Calatrava

Published: October 4, 2010
https://doi.org/10.1371/journal.pone.0013169

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Antivirals
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H1N1
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Influenza A virus
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Gene expression
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