Sulfated Dextrans Enhance In Vitro Amplification of Bovine Spongiform Encephalopathy PrP^Sc and Enable Ultrasensitive Detection of Bovine PrP^Sc

• Yuichi Murayama ,

  * E-mail: ymura@affrc.go.jp

  Affiliation Prion Disease Research Center, National Institute of Animal Health, Tsukuba, Japan

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• Miyako Yoshioka,

  Affiliations Prion Disease Research Center, National Institute of Animal Health, Tsukuba, Japan, Safety Research Team, National Institute of Animal Health, Tsukuba, Japan

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• Kentaro Masujin,

  Affiliation Prion Disease Research Center, National Institute of Animal Health, Tsukuba, Japan

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• Hiroyuki Okada,

  Affiliation Prion Disease Research Center, National Institute of Animal Health, Tsukuba, Japan

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• Yoshifumi Iwamaru,

  Affiliation Prion Disease Research Center, National Institute of Animal Health, Tsukuba, Japan

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• Morikazu Imamura,

  Affiliation Prion Disease Research Center, National Institute of Animal Health, Tsukuba, Japan

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• Yuichi Matsuura,

  Affiliation Prion Disease Research Center, National Institute of Animal Health, Tsukuba, Japan

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• Shigeo Fukuda,

  Affiliation Hokkaido Animal Research Center, Shintoku, Japan

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• Sadao Onoe,

  Affiliation Hokkaido Animal Research Center, Shintoku, Japan

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• Takashi Yokoyama,

  Affiliation Prion Disease Research Center, National Institute of Animal Health, Tsukuba, Japan

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• Shirou Mohri

  Affiliation Prion Disease Research Center, National Institute of Animal Health, Tsukuba, Japan

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