Light Chain Separated from the Rest of the Type A Botulinum Neurotoxin Molecule Is the Most Catalytically Active Form

Open Access

Peer-reviewed

Research Article

Nizamettin Gul,

Current address: Medical Identification and Treatment Systems (MITS) of Chemical Biological and Medical Systems (CBMS), Fort Detrick, Maryland, United States of America

Affiliation Integrated Toxicology Division, Department of Cell Biology and Biochemistry, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
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Leonard A. Smith,

Affiliations Integrated Toxicology Division, Department of Cell Biology and Biochemistry, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America, Medical Countermeasures Technology, United States Army Medical Research and Materiel Command, Fort Detrick, Maryland, United States of America
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S. Ashraf Ahmed

* E-mail: syed.ahmed@amedd.army.mil

Affiliation Integrated Toxicology Division, Department of Cell Biology and Biochemistry, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
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Botulinum toxin
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Fluorescence
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Tryptophan
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Cytosol
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Disulfide bonds
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Proteases
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Catalysts
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Toxins
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