Increase on the Initial Soluble Heme Levels in Acidic Conditions Is an Important Mechanism for Spontaneous Heme Crystallization In Vitro

• Renata Stiebler ,

  Contributed equally to this work with: Renata Stiebler, Anh N. Hoang

  Affiliation Laboratório de Bioquímica Redox, Programa de Biologia Molecular e Biotecnologia, Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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• Anh N. Hoang ,

  Contributed equally to this work with: Renata Stiebler, Anh N. Hoang

  Affiliation Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States of America

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• Timothy J. Egan ,

  * E-mail: maroli@bioqmed.ufrj.br (MFO); david.w.wright@vanderbilt.edu (DWW); timothy.egan@uct.ac.za (TJE)

  Affiliation Department of Chemistry, University of Cape Town, Rondebosch, South Africa

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• David W. Wright ,

  * E-mail: maroli@bioqmed.ufrj.br (MFO); david.w.wright@vanderbilt.edu (DWW); timothy.egan@uct.ac.za (TJE)

  Affiliation Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States of America

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• Marcus F. Oliveira

  * E-mail: maroli@bioqmed.ufrj.br (MFO); david.w.wright@vanderbilt.edu (DWW); timothy.egan@uct.ac.za (TJE)

  Affiliation Laboratório de Bioquímica Redox, Programa de Biologia Molecular e Biotecnologia, Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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