IL-2 Mediates CD4+ T Cell Help in the Breakdown of Memory-Like CD8+ T Cell Tolerance under Lymphopenic Conditions

Open Access

Peer-reviewed

Research Article

IL-2 Mediates CD4⁺ T Cell Help in the Breakdown of Memory-Like CD8⁺ T Cell Tolerance under Lymphopenic Conditions

Cécile Le Saout,

Affiliation Institut de Génétique Moléculaire de Montpellier, UMR 5535 Centre National de la Recherche Scientifique, Université Montpellier 2 and Université Montpellier 1, Montpellier, France
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Marine Villard,

Affiliation Institut de Génétique Moléculaire de Montpellier, UMR 5535 Centre National de la Recherche Scientifique, Université Montpellier 2 and Université Montpellier 1, Montpellier, France
⨯
Clémence Cabasse,

Affiliation Institut de Génétique Moléculaire de Montpellier, UMR 5535 Centre National de la Recherche Scientifique, Université Montpellier 2 and Université Montpellier 1, Montpellier, France
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Chantal Jacquet,

Affiliation Institut de Génétique Moléculaire de Montpellier, UMR 5535 Centre National de la Recherche Scientifique, Université Montpellier 2 and Université Montpellier 1, Montpellier, France
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Naomi Taylor,

Affiliation Institut de Génétique Moléculaire de Montpellier, UMR 5535 Centre National de la Recherche Scientifique, Université Montpellier 2 and Université Montpellier 1, Montpellier, France
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Javier Hernandez

* E-mail: javier.hernandez@igmm.cnrs.fr

Affiliation Institut de Génétique Moléculaire de Montpellier, UMR 5535 Centre National de la Recherche Scientifique, Université Montpellier 2 and Université Montpellier 1, Montpellier, France
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T cells
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Cytotoxic T cells
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Cloning
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Cell differentiation
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Pancreas
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Diabetes mellitus
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Genetically modified animals
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Autoimmunity
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