Gene Knock-Outs of Inositol 1,4,5-Trisphosphate Receptors Types 1 and 2 Result in Perturbation of Cardiogenesis

Keiko Uchida; Megumi Aramaki; Maki Nakazawa; Chihiro Yamagishi; Shinji Makino; Keiichi Fukuda; Takeshi Nakamura; Takao Takahashi; Katsuhiko Mikoshiba; Hiroyuki Yamagishi

doi:10.1371/journal.pone.0012500

Loading metrics

Open Access

Peer-reviewed

Research Article

Gene Knock-Outs of Inositol 1,4,5-Trisphosphate Receptors Types 1 and 2 Result in Perturbation of Cardiogenesis

Keiko Uchida ,

Contributed equally to this work with: Keiko Uchida, Megumi Aramaki

Affiliation Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan
⨯
Megumi Aramaki ,

Contributed equally to this work with: Keiko Uchida, Megumi Aramaki

Affiliation Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan
⨯
Maki Nakazawa,

Affiliation Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan
⨯
Chihiro Yamagishi,

Affiliation Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan
⨯
Shinji Makino,

Affiliation Department of Regenerative Medicine and Advanced Cardiac Therapeutics, Keio University School of Medicine, Tokyo, Japan
⨯
Keiichi Fukuda,

Affiliation Department of Regenerative Medicine and Advanced Cardiac Therapeutics, Keio University School of Medicine, Tokyo, Japan
⨯
Takeshi Nakamura †,

† Deceased.

Affiliation Calcium Oscillation Project, ICORP-SORST, Japan Science and Technology Agency, Saitama, Japan
⨯
Takao Takahashi,

Affiliation Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan
⨯
Katsuhiko Mikoshiba ,

* E-mail: mikosiba@brain.riken.jp (KM); hyamag@sc.itc.keio.ac.jp (HY)

Affiliations Calcium Oscillation Project, ICORP-SORST, Japan Science and Technology Agency, Saitama, Japan, Laboratory for Developmental Neurobiology, Brain Science Institute (BSI), RIKEN, Saitama, Japan
⨯
Hiroyuki Yamagishi

* E-mail: mikosiba@brain.riken.jp (KM); hyamag@sc.itc.keio.ac.jp (HY)

Affiliation Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan
⨯

Gene Knock-Outs of Inositol 1,4,5-Trisphosphate Receptors Types 1 and 2 Result in Perturbation of Cardiogenesis

Keiko Uchida,
Megumi Aramaki,
Maki Nakazawa,
Chihiro Yamagishi,
Shinji Makino,
Keiichi Fukuda,
Takeshi Nakamura,
Takao Takahashi,
Katsuhiko Mikoshiba,
Hiroyuki Yamagishi

Published: September 1, 2010
https://doi.org/10.1371/journal.pone.0012500

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cardiac ventricles
Is the Subject Area "Cardiac ventricles" applicable to this article?

Thanks for your feedback.
Calcineurin signaling cascade
Is the Subject Area "Calcineurin signaling cascade" applicable to this article?

Thanks for your feedback.
Heart
Is the Subject Area "Heart" applicable to this article?

Thanks for your feedback.
Zebrafish
Is the Subject Area "Zebrafish" applicable to this article?

Thanks for your feedback.
Cardiac atria
Is the Subject Area "Cardiac atria" applicable to this article?

Thanks for your feedback.
Intracellular receptors
Is the Subject Area "Intracellular receptors" applicable to this article?

Thanks for your feedback.
Developmental signaling
Is the Subject Area "Developmental signaling" applicable to this article?

Thanks for your feedback.
Cardiomyocytes
Is the Subject Area "Cardiomyocytes" applicable to this article?

Thanks for your feedback.