Regulatory T Cells Suppress Natural Killer Cells during Plasmid DNA Vaccination in Mice, Blunting the CD8+ T Cell Immune Response by the Cytokine TGFβ

Open Access

Peer-reviewed

Research Article

Regulatory T Cells Suppress Natural Killer Cells during Plasmid DNA Vaccination in Mice, Blunting the CD8⁺ T Cell Immune Response by the Cytokine TGFβ

Kwesi Frimpong-Boateng,

Affiliation Division of Viral Pathogenesis, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
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Nico van Rooijen,

Affiliation Department of Molecular Cell Biology, Vrije University Medical Center, Amsterdam, The Netherlands
⨯
Ralf Geiben-Lynn

* E-mail: rgeibenl@bidmc.harvard.edu

Affiliation Division of Viral Pathogenesis, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
⨯

Regulatory T cells
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T cells
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Immune response
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Cytotoxic T cells
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Antibodies
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DNA vaccination
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NK cells
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Vaccination and immunization
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