A Pandemic Influenza H1N1 Live Vaccine Based on Modified Vaccinia Ankara Is Highly Immunogenic and Protects Mice in Active and Passive Immunizations

Annett Hessel; Michael Schwendinger; Daniela Fritz; Sogue Coulibaly; Georg W. Holzer; Nicolas Sabarth; Otfried Kistner; Walter Wodal; Astrid Kerschbaum; Helga Savidis-Dacho; Brian A. Crowe; Thomas R. Kreil; P. Noel Barrett; Falko G. Falkner

doi:10.1371/journal.pone.0012217

Loading metrics

Open Access

Peer-reviewed

Research Article

A Pandemic Influenza H1N1 Live Vaccine Based on Modified Vaccinia Ankara Is Highly Immunogenic and Protects Mice in Active and Passive Immunizations

Annett Hessel,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Michael Schwendinger,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Daniela Fritz,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Sogue Coulibaly,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Georg W. Holzer,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Nicolas Sabarth,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Otfried Kistner,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Walter Wodal,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Astrid Kerschbaum,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Helga Savidis-Dacho,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Brian A. Crowe,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Thomas R. Kreil,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
P. Noel Barrett,

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯
Falko G. Falkner

* E-mail: falknef@baxter.com

Affiliation R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria
⨯

A Pandemic Influenza H1N1 Live Vaccine Based on Modified Vaccinia Ankara Is Highly Immunogenic and Protects Mice in Active and Passive Immunizations

Annett Hessel,
Michael Schwendinger,
Daniela Fritz,
Sogue Coulibaly,
Georg W. Holzer,
Nicolas Sabarth,
Otfried Kistner,
Walter Wodal,
Astrid Kerschbaum,
Helga Savidis-Dacho

Published: August 16, 2010
https://doi.org/10.1371/journal.pone.0012217

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Viral vaccines
Is the Subject Area "Viral vaccines" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
H1N1
Is the Subject Area "H1N1" applicable to this article?

Thanks for your feedback.
Influenza
Is the Subject Area "Influenza" applicable to this article?

Thanks for your feedback.
Influenza viruses
Is the Subject Area "Influenza viruses" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Swine influenza
Is the Subject Area "Swine influenza" applicable to this article?

Thanks for your feedback.