Hypoxia-Inducible Factor 1α Determines Gastric Cancer Chemosensitivity via Modulation of p53 and NF-κB

Nadine Rohwer; Christof Dame; Anja Haugstetter; Bertram Wiedenmann; Katharina Detjen; Clemens A. Schmitt; Thorsten Cramer

doi:10.1371/journal.pone.0012038

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Peer-reviewed

Research Article

Hypoxia-Inducible Factor 1α Determines Gastric Cancer Chemosensitivity via Modulation of p53 and NF-κB

Nadine Rohwer,

Affiliations Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin, Germany, Fachbereich Biologie, Chemie, Pharmazie, Freie Universität Berlin, Berlin, Germany, Molekulares Krebsforschungszentrum, Charité - Universitätsmedizin Berlin, Berlin, Germany
⨯
Christof Dame,

Affiliation Klinik für Neonatologie, Charité - Universitätsmedizin Berlin, Berlin, Germany
⨯
Anja Haugstetter,

Affiliations Molekulares Krebsforschungszentrum, Charité - Universitätsmedizin Berlin, Berlin, Germany, Max-Delbrück-Centrum für Molekulare Medizin, Berlin, Germany
⨯
Bertram Wiedenmann,

Affiliation Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin, Germany
⨯
Katharina Detjen,

Affiliations Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin, Germany, Molekulares Krebsforschungszentrum, Charité - Universitätsmedizin Berlin, Berlin, Germany
⨯
Clemens A. Schmitt,

Affiliations Molekulares Krebsforschungszentrum, Charité - Universitätsmedizin Berlin, Berlin, Germany, Max-Delbrück-Centrum für Molekulare Medizin, Berlin, Germany
⨯
Thorsten Cramer

* E-mail: thorsten.cramer@charite.de

Affiliations Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin, Germany, Molekulares Krebsforschungszentrum, Charité - Universitätsmedizin Berlin, Berlin, Germany
⨯

Hypoxia-Inducible Factor 1α Determines Gastric Cancer Chemosensitivity via Modulation of p53 and NF-κB

Nadine Rohwer,
Christof Dame,
Anja Haugstetter,
Bertram Wiedenmann,
Katharina Detjen,
Clemens A. Schmitt,
Thorsten Cramer

Published: August 10, 2010
https://doi.org/10.1371/journal.pone.0012038

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