Fluidization and Resolidification of the Human Bladder Smooth Muscle Cell in Response to Transient Stretch

Cheng Chen; Ramaswamy Krishnan; Enhua Zhou; Aruna Ramachandran; Dhananjay Tambe; Kavitha Rajendran; Rosalyn M. Adam; Linhong Deng; Jeffrey J. Fredberg

doi:10.1371/journal.pone.0012035

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Open Access

Peer-reviewed

Research Article

Fluidization and Resolidification of the Human Bladder Smooth Muscle Cell in Response to Transient Stretch

Cheng Chen ,

Contributed equally to this work with: Cheng Chen, Ramaswamy Krishnan

Affiliations Key Laboratory of Biorheological Science and Technology, Ministry of Education, Bioengineering College, Chongqing University, Chongqing, China, Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯
Ramaswamy Krishnan ,

Contributed equally to this work with: Cheng Chen, Ramaswamy Krishnan

Affiliation Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯
Enhua Zhou,

Affiliation Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯
Aruna Ramachandran,

Affiliation Urological Diseases Research Center, Department of Urology, Children's Hospital Boston and Department of Surgery, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Dhananjay Tambe,

Affiliation Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯
Kavitha Rajendran,

Affiliation Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯
Rosalyn M. Adam,

Affiliation Urological Diseases Research Center, Department of Urology, Children's Hospital Boston and Department of Surgery, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Linhong Deng ,

* E-mail: denglh@cqu.edu.cn

Affiliations Key Laboratory of Biorheological Science and Technology, Ministry of Education, Bioengineering College, Chongqing University, Chongqing, China, Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯
Jeffrey J. Fredberg

Affiliation Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯

Fluidization and Resolidification of the Human Bladder Smooth Muscle Cell in Response to Transient Stretch

Cheng Chen,
Ramaswamy Krishnan,
Enhua Zhou,
Aruna Ramachandran,
Dhananjay Tambe,
Kavitha Rajendran,
Rosalyn M. Adam,
Linhong Deng,
Jeffrey J. Fredberg

Published: August 6, 2010
https://doi.org/10.1371/journal.pone.0012035

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Actins
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Cytoskeleton
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Bladder
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Elasticity
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Polyacrylamides
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Smooth muscle cells
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Stiffness
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