The 4q12 Amplicon in Malignant Peripheral Nerve Sheath Tumors: Consequences on Gene Expression and Implications for Sunitinib Treatment

Open Access

Peer-reviewed

Research Article

Jan Zietsch,

Affiliation Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany
⨯
Nicolas Ziegenhagen,

Affiliation Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany
⨯
Frank L. Heppner,

Affiliation Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany
⨯
David Reuss,

Affiliation Department of Neuropathology, Ruprecht-Karls-University Heidelberg, and Deutsches Krebsforschungszentrum Heidelberg, Heidelberg, Germany
⨯
Andreas von Deimling,

Affiliation Department of Neuropathology, Ruprecht-Karls-University Heidelberg, and Deutsches Krebsforschungszentrum Heidelberg, Heidelberg, Germany
⨯
Nikola Holtkamp

* E-mail: nikola.holtkamp@charite.de

Affiliation Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany
⨯

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Malignant tumors
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Signal amplification
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Cultured fibroblasts
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VEGF signaling
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