SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kγ Activity through Deacetylation of Specific Lysine Residues in Mammals

• Sayaka Akieda-Asai,

  Affiliations Frontier Science Research Center, University of Miyazaki, Miyazaki, Japan, Mitsubishi Kagaku Institute of Life Sciences (MITILS), Tokyo, Japan

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• Nobuhiro Zaima,

  Affiliations Mitsubishi Kagaku Institute of Life Sciences (MITILS), Tokyo, Japan, Department of Molecular Anatomy, Hamamatsu University School of Medicine, Shizuoka, Japan

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• Koji Ikegami,

  Affiliations Mitsubishi Kagaku Institute of Life Sciences (MITILS), Tokyo, Japan, Department of Molecular Anatomy, Hamamatsu University School of Medicine, Shizuoka, Japan

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• Tomoaki Kahyo,

  Affiliations Mitsubishi Kagaku Institute of Life Sciences (MITILS), Tokyo, Japan, Department of Pathology, Hamamatsu University School of Medicine, Shizuoka, Japan

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• Ikuko Yao,

  Affiliations Mitsubishi Kagaku Institute of Life Sciences (MITILS), Tokyo, Japan, Department of Medical Chemistry, Kansai Medical University, Osaka, Japan

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• Takahiro Hatanaka,

  Affiliation Mitsubishi Kagaku Institute of Life Sciences (MITILS), Tokyo, Japan

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• Shun-ichiro Iemura,

  Affiliation National Institute of Advanced Industrial Science and Technology, Biomedicinal Information Research Center, Tokyo, Japan

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• Rika Sugiyama,

  Affiliation Department of Physiological Chemistry, Graduate School of Comprehensive Human Sciences and Institute of Basic Medical Sciences, University of Tsukuba, Ibaraki, Japan

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• Takeaki Yokozeki,

  Affiliation Department of Physiological Chemistry, Graduate School of Comprehensive Human Sciences and Institute of Basic Medical Sciences, University of Tsukuba, Ibaraki, Japan

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• Yoshinobu Eishi,

  Affiliation Department of Human Pathology, Tokyo Medical and Dental University, Tokyo, Japan

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• Morio Koike,

  Affiliation Department of Human Pathology, Tokyo Medical and Dental University, Tokyo, Japan

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• Kyoji Ikeda,

  Affiliation Department of Bone and Joint Disease, Research Institute, National Center for Geriatrics and Gerontology, Aichi, Japan

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• Takuya Chiba,

  Affiliation Department of Investigative Pathology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

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• Haruyoshi Yamaza,

  Affiliations Department of Investigative Pathology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, Section of Pediatric Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan

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• Isao Shimokawa,

  Affiliation Department of Investigative Pathology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

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• Si-Young Song,

  Affiliation Mitsubishi Kagaku Institute of Life Sciences (MITILS), Tokyo, Japan

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• Akira Matsuno,

  Affiliation Department of Neurosurgery, Teikyo University Chica Medical Center, Chiba, Japan

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• Akiko Mizutani,

  Affiliation Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Kanagawa, Japan

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• Motoji Sawabe,

  Affiliation Department of Pathology and Bioresource Center for Geriatric Research, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan

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• Moses V. Chao,

  Affiliation Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, New York, United States of America

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• Masashi Tanaka,

  Affiliation Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan

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• Yasunori Kanaho,

  Affiliation Department of Physiological Chemistry, Graduate School of Comprehensive Human Sciences and Institute of Basic Medical Sciences, University of Tsukuba, Ibaraki, Japan

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• Tohru Natsume,

  Affiliation National Institute of Advanced Industrial Science and Technology, Biomedicinal Information Research Center, Tokyo, Japan

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• Haruhiko Sugimura,

  Affiliation Department of Pathology, Hamamatsu University School of Medicine, Shizuoka, Japan

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• Yukari Date,

  Affiliation Frontier Science Research Center, University of Miyazaki, Miyazaki, Japan

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• Michael W. McBurney,

  Affiliation Ottawa Hospital Research Institute and Department of Medicine, University of Ottawa, Ottawa, Canada

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• Leonard Guarente,

  Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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•  [ ... ],
• Mitsutoshi Setou

  * E-mail: setou@hama-med.ac.jp

  Affiliations Mitsubishi Kagaku Institute of Life Sciences (MITILS), Tokyo, Japan, Department of Molecular Anatomy, Hamamatsu University School of Medicine, Shizuoka, Japan

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