Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

Xingxing Kong; Rui Wang; Yuan Xue; Xiaojun Liu; Huabing Zhang; Yong Chen; Fude Fang; Yongsheng Chang

doi:10.1371/journal.pone.0011707

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Peer-reviewed

Research Article

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

Xingxing Kong,

Affiliation The National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Rui Wang,

Affiliation The National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Yuan Xue,

Affiliation Hubei Province Key Laboratory of Biotechnology of Chinese Traditional Medicine, Hubei University, Wuhan, China
⨯
Xiaojun Liu,

Affiliation The National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Huabing Zhang,

Affiliation The National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Yong Chen ,

* E-mail: cy101610@npc.gov.cn (Y. Chen); fangfd@vip.sina.com (FF); changy@ibms.pumc.edu.cn (Y. Chang)

Affiliation Hubei Province Key Laboratory of Biotechnology of Chinese Traditional Medicine, Hubei University, Wuhan, China
⨯
Fude Fang ,

* E-mail: cy101610@npc.gov.cn (Y. Chen); fangfd@vip.sina.com (FF); changy@ibms.pumc.edu.cn (Y. Chang)

Affiliation The National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Yongsheng Chang

* E-mail: cy101610@npc.gov.cn (Y. Chen); fangfd@vip.sina.com (FF); changy@ibms.pumc.edu.cn (Y. Chang)

Affiliation The National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

Xingxing Kong,
Rui Wang,
Yuan Xue,
Xiaojun Liu,
Huabing Zhang,
Yong Chen,
Fude Fang,
Yongsheng Chang

Published: July 22, 2010
https://doi.org/10.1371/journal.pone.0011707

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