Reduced Body Weight and Increased Energy Expenditure in Transgenic Mice Over-Expressing Soluble Leptin Receptor

Phing-How Lou; Guoqing Yang; Lu Huang; Yunxia Cui; Tiffany Pourbahrami; George K. Radda; Cai Li; Weiping Han

doi:10.1371/journal.pone.0011669

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Open Access

Peer-reviewed

Research Article

Reduced Body Weight and Increased Energy Expenditure in Transgenic Mice Over-Expressing Soluble Leptin Receptor

Phing-How Lou,

Affiliation Laboratory of Metabolic Medicine, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore
⨯
Guoqing Yang,

Affiliation Laboratory of Metabolic Medicine, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore
⨯
Lu Huang,

Affiliation Department of Physiology, Touchstone Center for Diabetes Research, The University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Yunxia Cui,

Affiliation Department of Physiology, Touchstone Center for Diabetes Research, The University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Tiffany Pourbahrami,

Affiliation Department of Physiology, Touchstone Center for Diabetes Research, The University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
George K. Radda,

Affiliation Laboratory of Metabolic Medicine, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore
⨯
Cai Li ,

* E-mail: cai_li@merck.com (CL); weiping_han@sbic.a-star.edu.sg (WH)

Current address: Department of Diabetes and Obesity, Merck Research Laboratories, Rahway, New Jersey, United States of America

Affiliation Department of Physiology, Touchstone Center for Diabetes Research, The University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Weiping Han

* E-mail: cai_li@merck.com (CL); weiping_han@sbic.a-star.edu.sg (WH)

Affiliations Laboratory of Metabolic Medicine, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore, Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯

Reduced Body Weight and Increased Energy Expenditure in Transgenic Mice Over-Expressing Soluble Leptin Receptor

Phing-How Lou,
Guoqing Yang,
Lu Huang,
Yunxia Cui,
Tiffany Pourbahrami,
George K. Radda,
Cai Li,
Weiping Han

Published: July 20, 2010
https://doi.org/10.1371/journal.pone.0011669

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