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Open Access

Peer-reviewed

Research Article

MMP-9, uPAR and Cathepsin B Silencing Downregulate Integrins in Human Glioma Xenograft Cells In Vitro and In Vivo in Nude Mice

Krishna Kumar Veeravalli,

Affiliation Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States of America
⨯
Chandramu Chetty,

Affiliation Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States of America
⨯
Shivani Ponnala,

Affiliation Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States of America
⨯
Christopher S. Gondi,

Affiliation Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States of America
⨯
Sajani S. Lakka,

Affiliation Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States of America
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Daniel Fassett,

Affiliation Department Neurosurgery, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States of America
⨯
Jeffrey D. Klopfenstein,

Affiliation Department Neurosurgery, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States of America
⨯
Dzung H. Dinh,

Affiliation Department Neurosurgery, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States of America
⨯
Meena Gujrati,

Affiliation Department Pathology, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States of America
⨯
Jasti S. Rao

* E-mail: jsrao@uic.edu

Affiliations Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States of America, Department Neurosurgery, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States of America
⨯

MMP-9, uPAR and Cathepsin B Silencing Downregulate Integrins in Human Glioma Xenograft Cells In Vitro and In Vivo in Nude Mice

Krishna Kumar Veeravalli,
Chandramu Chetty,
Shivani Ponnala,
Christopher S. Gondi,
Sajani S. Lakka,
Daniel Fassett,
Jeffrey D. Klopfenstein,
Dzung H. Dinh,
Meena Gujrati,
Jasti S. Rao

x

Published: July 15, 2010
https://doi.org/10.1371/journal.pone.0011583

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Integrins
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Cancer treatment
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Transfection
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Glioma cells
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Plasmid construction
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Cancers and neoplasms
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Cell migration
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Wound healing
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