Histone Deacetylase 3 Depletion in Osteo/Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat

David F. Razidlo; Tiffany J. Whitney; Michelle E. Casper; Meghan E. McGee-Lawrence; Bridget A. Stensgard; Xiaodong Li; Frank J. Secreto; Sarah K. Knutson; Scott W. Hiebert; Jennifer J. Westendorf

doi:10.1371/journal.pone.0011492

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Peer-reviewed

Research Article

Histone Deacetylase 3 Depletion in Osteo/Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat

David F. Razidlo ,

Contributed equally to this work with: David F. Razidlo, Tiffany J. Whitney

Affiliation Department of Orthopedic Surgery and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Tiffany J. Whitney ,

Contributed equally to this work with: David F. Razidlo, Tiffany J. Whitney

Affiliation Department of Orthopedic Surgery and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Michelle E. Casper,

Affiliation Department of Orthopedic Surgery and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Meghan E. McGee-Lawrence,

Affiliation Department of Orthopedic Surgery and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Bridget A. Stensgard,

Affiliation Department of Orthopedic Surgery and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Xiaodong Li,

Affiliation Department of Orthopedic Surgery and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Frank J. Secreto,

Affiliation Department of Orthopedic Surgery and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Sarah K. Knutson,

Affiliation Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, United States of America
⨯
Scott W. Hiebert,

Affiliation Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, United States of America
⨯
Jennifer J. Westendorf

* E-mail: westendorf.jennifer@mayo.edu

Affiliation Department of Orthopedic Surgery and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯

Histone Deacetylase 3 Depletion in Osteo/Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat

David F. Razidlo,
Tiffany J. Whitney,
Michelle E. Casper,
Meghan E. McGee-Lawrence,
Bridget A. Stensgard,
Xiaodong Li,
Frank J. Secreto,
Sarah K. Knutson,
Scott W. Hiebert,
Jennifer J. Westendorf

Published: July 9, 2010
https://doi.org/10.1371/journal.pone.0011492

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