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Open Access

Peer-reviewed

Research Article

Src Kinases Are Required for a Balanced Production of IL-12/IL-23 in Human Dendritic Cells Activated by Toll-Like Receptor Agonists

Mirela Kuka,

Current address: National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Affiliation Novartis Vaccines, Siena, Italy
⨯
Roberta Baronio,

Current address: Institute for Genomics and Bioinformatics, University of California Irvine, Irvine, California, United States of America

Affiliation Novartis Vaccines, Siena, Italy
⨯
Sara Valentini,

Affiliation Novartis Vaccines, Siena, Italy
⨯
Elisabetta Monaci,

Affiliation Novartis Vaccines, Siena, Italy
⨯
Alessandro Muzzi,

Affiliation Novartis Vaccines, Siena, Italy
⨯
Susanna Aprea,

Affiliation Novartis Vaccines, Siena, Italy
⨯
Ennio De Gregorio,

Affiliation Novartis Vaccines, Siena, Italy
⨯
Ugo D'Oro

* E-mail: ugo.doro@novartis.com

Affiliation Novartis Vaccines, Siena, Italy
⨯

Src Kinases Are Required for a Balanced Production of IL-12/IL-23 in Human Dendritic Cells Activated by Toll-Like Receptor Agonists

Mirela Kuka,
Roberta Baronio,
Sara Valentini,
Elisabetta Monaci,
Alessandro Muzzi,
Susanna Aprea,
Ennio De Gregorio,
Ugo D'Oro

x

Published: July 9, 2010
https://doi.org/10.1371/journal.pone.0011491

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Protein kinases
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Cytokines
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T cells
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Cell differentiation
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Toll-like receptors
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Transcription factors
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Inflammation
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T helper cells
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