Inhibition of the Progesterone Nuclear Receptor during the Bone Linear Growth Phase Increases Peak Bone Mass in Female Mice

Wei Yao; Weiwei Dai; Mohammad Shahnazari; Aaron Pham; Zhiqiang Chen; Haiyan Chen; Min Guan; Nancy E. Lane

doi:10.1371/journal.pone.0011410

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Open Access

Peer-reviewed

Research Article

Inhibition of the Progesterone Nuclear Receptor during the Bone Linear Growth Phase Increases Peak Bone Mass in Female Mice

Wei Yao ,

* E-mail: wei.yao@ucdmc.ucdavis.edu

Affiliation Department of Internal Medicine, Center for Healthy Aging, University of California Davis Medical Center, Sacramento, California, United States of America
⨯
Weiwei Dai,

Affiliation Department of Internal Medicine, Center for Healthy Aging, University of California Davis Medical Center, Sacramento, California, United States of America
⨯
Mohammad Shahnazari,

Affiliation Department of Internal Medicine, Center for Healthy Aging, University of California Davis Medical Center, Sacramento, California, United States of America
⨯
Aaron Pham,

Affiliation Department of Internal Medicine, Center for Healthy Aging, University of California Davis Medical Center, Sacramento, California, United States of America
⨯
Zhiqiang Chen,

Affiliation Department of Internal Medicine, Center for Healthy Aging, University of California Davis Medical Center, Sacramento, California, United States of America
⨯
Haiyan Chen,

Affiliation Department of Internal Medicine, Center for Healthy Aging, University of California Davis Medical Center, Sacramento, California, United States of America
⨯
Min Guan,

Affiliation Department of Internal Medicine, Center for Healthy Aging, University of California Davis Medical Center, Sacramento, California, United States of America
⨯
Nancy E. Lane

Affiliation Department of Internal Medicine, Center for Healthy Aging, University of California Davis Medical Center, Sacramento, California, United States of America
⨯

Inhibition of the Progesterone Nuclear Receptor during the Bone Linear Growth Phase Increases Peak Bone Mass in Female Mice

Wei Yao,
Weiwei Dai,
Mohammad Shahnazari,
Aaron Pham,
Zhiqiang Chen,
Haiyan Chen,
Min Guan,
Nancy E. Lane

Published: July 1, 2010
https://doi.org/10.1371/journal.pone.0011410

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Osteoclasts
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Progesterone
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Bone development
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Osteoblasts
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Bone resorption
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Gene expression
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