Protein-Protein Interaction Antagonists as Novel Inhibitors of Non-Canonical Polyubiquitylation

Johanna Scheper; Marta Guerra-Rebollo; Glòria Sanclimens; Alejandra Moure; Isabel Masip; Domingo González-Ruiz; Nuria Rubio; Bernat Crosas; Óscar Meca-Cortés; Noureddine Loukili; Vanessa Plans; Antonio Morreale; Jerónimo Blanco; Angel R. Ortiz; Àngel Messeguer; Timothy M. Thomson

doi:10.1371/journal.pone.0011403

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Open Access

Peer-reviewed

Research Article

Protein-Protein Interaction Antagonists as Novel Inhibitors of Non-Canonical Polyubiquitylation

Johanna Scheper ,

Contributed equally to this work with: Johanna Scheper, Marta Guerra-Rebollo

Affiliation Department of Cell Biology, Institute for Molecular Biology (IBMB-CSIC), Barcelona, Spain
⨯
Marta Guerra-Rebollo ,

Contributed equally to this work with: Johanna Scheper, Marta Guerra-Rebollo

Affiliation Department of Cell Biology, Institute for Molecular Biology (IBMB-CSIC), Barcelona, Spain
⨯
Glòria Sanclimens,

Affiliation Department of Biological Organic Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain
⨯
Alejandra Moure,

Affiliation Department of Biological Organic Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain
⨯
Isabel Masip,

Affiliation Department of Biological Organic Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain
⨯
Domingo González-Ruiz,

Affiliation Bioinformatics Unit, Centro de Biología Molecular Severo Ochoa (CBM-UAM-CSIC), Madrid, Spain
⨯
Nuria Rubio,

Affiliation Catalan Center for Cardiovascular Research (CIC-CSIC), and CIBER de Bioingeniería, Biomateriales y Nanomedicina, Barcelona, Spain
⨯
Bernat Crosas,

Affiliation Department of Cell Biology, Institute for Molecular Biology (IBMB-CSIC), Barcelona, Spain
⨯
Óscar Meca-Cortés,

Affiliation Department of Cell Biology, Institute for Molecular Biology (IBMB-CSIC), Barcelona, Spain
⨯
Noureddine Loukili,

Affiliation Department of Cell Biology, Institute for Molecular Biology (IBMB-CSIC), Barcelona, Spain
⨯
Vanessa Plans,

Affiliation Department of Cell Biology, Institute for Molecular Biology (IBMB-CSIC), Barcelona, Spain
⨯
Antonio Morreale,

Affiliation Bioinformatics Unit, Centro de Biología Molecular Severo Ochoa (CBM-UAM-CSIC), Madrid, Spain
⨯
Jerónimo Blanco,

Affiliation Catalan Center for Cardiovascular Research (CIC-CSIC), and CIBER de Bioingeniería, Biomateriales y Nanomedicina, Barcelona, Spain
⨯
Angel R. Ortiz,

Affiliation Bioinformatics Unit, Centro de Biología Molecular Severo Ochoa (CBM-UAM-CSIC), Madrid, Spain
⨯
Àngel Messeguer,

Affiliation Department of Biological Organic Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain
⨯
[ ... ],
Timothy M. Thomson

* E-mail: titbmc@cid.csic.es

Affiliation Department of Cell Biology, Institute for Molecular Biology (IBMB-CSIC), Barcelona, Spain
⨯
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Protein-Protein Interaction Antagonists as Novel Inhibitors of Non-Canonical Polyubiquitylation

Johanna Scheper,
Marta Guerra-Rebollo,
Glòria Sanclimens,
Alejandra Moure,
Isabel Masip,
Domingo González-Ruiz,
Nuria Rubio,
Bernat Crosas,
Óscar Meca-Cortés,
Noureddine Loukili

Published: June 30, 2010
https://doi.org/10.1371/journal.pone.0011403

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