A General Model for Multilocus Epistatic Interactions in Case-Control Studies

Open Access

Peer-reviewed

Research Article

Zhong Wang,

Affiliations Center for Statistical Genetics, Pennsylvania State University, Hershey, Pennsylvania, United States of America, Pennsylvania State Cancer Institute, Pennsylvania State University, Hershey, Pennsylvania, United States of America
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Tian Liu,

Affiliation Human Genetics Group, Genome Institute of Singapore, Singapore, Singapore
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Zhenwu Lin,

Affiliation Department of Surgery, Pennsylvania State University, Hershey, Pennsylvania, United States of America
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John Hegarty,

Affiliation Department of Surgery, Pennsylvania State University, Hershey, Pennsylvania, United States of America
⨯
Walter A. Koltun,

Affiliation Department of Surgery, Pennsylvania State University, Hershey, Pennsylvania, United States of America
⨯
Rongling Wu

* E-mail: rwu@hes.hmc.psu.edu

Affiliations Center for Statistical Genetics, Pennsylvania State University, Hershey, Pennsylvania, United States of America, Pennsylvania State Cancer Institute, Pennsylvania State University, Hershey, Pennsylvania, United States of America
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Epistasis
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Genetic loci
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Single nucleotide polymorphisms
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Fitness epistasis
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Genetics of disease
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Genetics
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Test statistics
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Variant genotypes
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