Low Doses of Ionizing Radiation Promote Tumor Growth and Metastasis by Enhancing Angiogenesis

Inês Sofia Vala; Leila R. Martins; Natsuko Imaizumi; Raquel J. Nunes; José Rino; François Kuonen; Lara M. Carvalho; Curzio Rüegg; Isabel Monteiro Grillo; João Taborda Barata; Marc Mareel; Susana Constantino Rosa Santos

doi:10.1371/journal.pone.0011222

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Peer-reviewed

Research Article

Low Doses of Ionizing Radiation Promote Tumor Growth and Metastasis by Enhancing Angiogenesis

Inês Sofia Vala,

Affiliation Angiogenesis Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
⨯
Leila R. Martins,

Affiliation Cancer Biology Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
⨯
Natsuko Imaizumi,

Affiliation Division of Experimental Oncology, Centre Pluridisciplinaire d'Oncologie, Faculty of Biology and Medicine, University of Lausanne, and NCCR Molecular Oncology ISREC-EPFL, Epalinges, Switzerland
⨯
Raquel J. Nunes,

Affiliation Angiogenesis Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
⨯
José Rino,

Affiliation Bioimaging Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
⨯
François Kuonen,

Affiliation Division of Experimental Oncology, Centre Pluridisciplinaire d'Oncologie, Faculty of Biology and Medicine, University of Lausanne, and NCCR Molecular Oncology ISREC-EPFL, Epalinges, Switzerland
⨯
Lara M. Carvalho,

Affiliation Zebrafish Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
⨯
Curzio Rüegg,

Affiliation Division of Experimental Oncology, Centre Pluridisciplinaire d'Oncologie, Faculty of Biology and Medicine, University of Lausanne, and NCCR Molecular Oncology ISREC-EPFL, Epalinges, Switzerland
⨯
Isabel Monteiro Grillo,

Affiliation Serviço de Radioterapia do Hospital de Santa Maria, Lisbon, Portugal and Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
⨯
João Taborda Barata,

Affiliation Cancer Biology Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
⨯
Marc Mareel,

Affiliation Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
⨯
Susana Constantino Rosa Santos

* E-mail: sconstantino@fm.ul.pt

Affiliation Angiogenesis Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
⨯

Low Doses of Ionizing Radiation Promote Tumor Growth and Metastasis by Enhancing Angiogenesis

Inês Sofia Vala,
Leila R. Martins,
Natsuko Imaizumi,
Raquel J. Nunes,
José Rino,
François Kuonen,
Lara M. Carvalho,
Curzio Rüegg,
Isabel Monteiro Grillo,
João Taborda Barata

Published: June 21, 2010
https://doi.org/10.1371/journal.pone.0011222

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