Alu Sequences in Undifferentiated Human Embryonic Stem Cells Display High Levels of A-to-I RNA Editing

Sivan Osenberg; Nurit Paz Yaacov; Michal Safran; Sharon Moshkovitz; Ronit Shtrichman; Ofra Sherf; Jasmine Jacob-Hirsch; Gilmor Keshet; Ninette Amariglio; Joseph Itskovitz-Eldor; Gideon Rechavi

doi:10.1371/journal.pone.0011173

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Open Access

Peer-reviewed

Research Article

Alu Sequences in Undifferentiated Human Embryonic Stem Cells Display High Levels of A-to-I RNA Editing

Sivan Osenberg,

Affiliations Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Nurit Paz Yaacov,

Affiliations Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Michal Safran,

Affiliation Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel
⨯
Sharon Moshkovitz,

Affiliation Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel
⨯
Ronit Shtrichman,

Affiliation Sohnis and Forman Families Stem Cell Center, Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
⨯
Ofra Sherf,

Affiliation Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel
⨯
Jasmine Jacob-Hirsch,

Affiliation Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel
⨯
Gilmor Keshet,

Affiliation Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel
⨯
Ninette Amariglio ,

* E-mail: Ninette.Amariglio@sheba.health.gov.il

Affiliation Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel
⨯
Joseph Itskovitz-Eldor,

Affiliations Sohnis and Forman Families Stem Cell Center, Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel, Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel
⨯
Gideon Rechavi

Affiliations Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯

Alu Sequences in Undifferentiated Human Embryonic Stem Cells Display High Levels of A-to-I RNA Editing

Sivan Osenberg,
Nurit Paz Yaacov,
Michal Safran,
Sharon Moshkovitz,
Ronit Shtrichman,
Ofra Sherf,
Jasmine Jacob-Hirsch,
Gilmor Keshet,
Ninette Amariglio,
Joseph Itskovitz-Eldor

Published: June 21, 2010
https://doi.org/10.1371/journal.pone.0011173

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Neuronal differentiation
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Alu elements
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Gene expression
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Small interfering RNA
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RNA editing
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Cell differentiation
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Transfection
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RNA analysis
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