Hypoxia Activates the K-Ras Proto-Oncogene to Stimulate Angiogenesis and Inhibit Apoptosis in Colon Cancer Cells

Open Access

Peer-reviewed

Research Article

Min Zeng,

Affiliation Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
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Hirotoshi Kikuchi,

Affiliation Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
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Maria S. Pino,

Affiliation Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Daniel C. Chung

* E-mail: dchung@partners.org.

Affiliation Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
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Hypoxia
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Small interfering RNA
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Caco-2 cells
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Apoptosis
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Transfection
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Colorectal cancer
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Malignant tumors
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HT29 cells
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