Structural and Dynamical Effects Induced by the Anticancer Drug Topotecan on the Human Topoisomerase I – DNA Complex

• Giordano Mancini,

  Affiliation CASPUR Inter-University Consortium for the Application of Super-Computing for Universities and Research, Rome, Italy

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• Ilda D'Annessa,

  Affiliations CASPUR Inter-University Consortium for the Application of Super-Computing for Universities and Research, Rome, Italy, Department of Biology and Centro di Bioinformatica e Biostatistica, University of Rome Tor Vergata, Rome, Italy

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• Andrea Coletta,

  Affiliation Department of Biology and Centro di Bioinformatica e Biostatistica, University of Rome Tor Vergata, Rome, Italy

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• Nico Sanna,

  Affiliation CASPUR Inter-University Consortium for the Application of Super-Computing for Universities and Research, Rome, Italy

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• Giovanni Chillemi ,

  * E-mail: g.chillemi@caspur.it (GC); desideri@uniroma2.it (AD)

  Affiliation CASPUR Inter-University Consortium for the Application of Super-Computing for Universities and Research, Rome, Italy

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• Alessandro Desideri

  * E-mail: g.chillemi@caspur.it (GC); desideri@uniroma2.it (AD)

  Affiliation Department of Biology and Centro di Bioinformatica e Biostatistica, University of Rome Tor Vergata, Rome, Italy

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