Haplotype Analysis Reveals a Possible Founder Effect of RET Mutation R114H for Hirschsprung's Disease in the Chinese Population

Belinda K. Cornes; Clara S. Tang; Thomas Y. Y. Leon; Kenneth J. W. S. Hui; Man-Ting So; Xiaoping Miao; Stacey S. Cherny; Pak C. Sham; Paul K. H. Tam; Maria-Merce Garcia-Barcelo

doi:10.1371/journal.pone.0010918

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Open Access

Peer-reviewed

Research Article

Haplotype Analysis Reveals a Possible Founder Effect of RET Mutation R114H for Hirschsprung's Disease in the Chinese Population

Belinda K. Cornes,

Affiliation Paediatric Surgery Division, Department of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China
⨯
Clara S. Tang,

Affiliation Department of Psychiatry, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China
⨯
Thomas Y. Y. Leon,

Affiliation Paediatric Surgery Division, Department of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China
⨯
Kenneth J. W. S. Hui,

Affiliation Paediatric Surgery Division, Department of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China
⨯
Man-Ting So,

Affiliation Paediatric Surgery Division, Department of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China
⨯
Xiaoping Miao,

Affiliation Paediatric Surgery Division, Department of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China
⨯
Stacey S. Cherny,

Affiliation Department of Psychiatry, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China
⨯
Pak C. Sham,

Affiliation Department of Psychiatry, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China
⨯
Paul K. H. Tam,

Affiliation Paediatric Surgery Division, Department of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China
⨯
Maria-Merce Garcia-Barcelo

* E-mail: mmgarcia@hkucc.hku.hk

Affiliation Paediatric Surgery Division, Department of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China
⨯

Haplotype Analysis Reveals a Possible Founder Effect of RET Mutation R114H for Hirschsprung's Disease in the Chinese Population

Belinda K. Cornes,
Clara S. Tang,
Thomas Y. Y. Leon,
Kenneth J. W. S. Hui,
Man-Ting So,
Xiaoping Miao,
Stacey S. Cherny,
Pak C. Sham,
Paul K. H. Tam,
Maria-Merce Garcia-Barcelo

Published: June 2, 2010
https://doi.org/10.1371/journal.pone.0010918

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