Multiple Phosphatidylinositol 3-Kinases Regulate Vaccinia Virus Morphogenesis

Shannon McNulty; William Bornmann; Jill Schriewer; Chas Werner; Scott K. Smith; Victoria A. Olson; Inger K. Damon; R. Mark Buller; John Heuser; Daniel Kalman

doi:10.1371/journal.pone.0010884

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Peer-reviewed

Research Article

Multiple Phosphatidylinositol 3-Kinases Regulate Vaccinia Virus Morphogenesis

Shannon McNulty,

Affiliation Microbiology and Molecular Genetics Graduate Program, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
William Bornmann,

Affiliation MD Anderson Cancer Center, University of Texas, Houston, Texas, United States of America
⨯
Jill Schriewer,

Affiliation Department of Molecular Microbiology and Immunology, Saint Louis University Health Sciences Center, St. Louis, Missouri, United States of America
⨯
Chas Werner,

Affiliation Department of Molecular Microbiology and Immunology, Saint Louis University Health Sciences Center, St. Louis, Missouri, United States of America
⨯
Scott K. Smith,

Affiliation Poxvirus Team, Poxvirus and Rabies Branch, Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Viral and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Victoria A. Olson,

Affiliation Poxvirus Team, Poxvirus and Rabies Branch, Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Viral and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Inger K. Damon,

Affiliation Poxvirus Team, Poxvirus and Rabies Branch, Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Viral and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
R. Mark Buller,

Affiliation Department of Molecular Microbiology and Immunology, Saint Louis University Health Sciences Center, St. Louis, Missouri, United States of America
⨯
John Heuser,

Affiliation Department of Cell Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Daniel Kalman

* E-mail: dkalman@emory.edu

Affiliation Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯

Multiple Phosphatidylinositol 3-Kinases Regulate Vaccinia Virus Morphogenesis

Shannon McNulty,
William Bornmann,
Jill Schriewer,
Chas Werner,
Scott K. Smith,
Victoria A. Olson,
Inger K. Damon,
R. Mark Buller,
John Heuser,
Daniel Kalman

Published: May 28, 2010
https://doi.org/10.1371/journal.pone.0010884

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Virions
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Morphogenesis
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Actins
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Cell membranes
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Vaccinia virus
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BHK cells
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Cell disruption
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