Effects of MDM2, MDM4 and TP53 Codon 72 Polymorphisms on Cancer Risk in a Cohort Study of Carriers of TP53 Germline Mutations

Shenying Fang; Ralf Krahe; Guillermina Lozano; Younghun Han; Wei Chen; Sean M. Post; Baili Zhang; Charmaine D. Wilson; Linda L. Bachinski; Louise C. Strong; Christopher I. Amos

doi:10.1371/journal.pone.0010813

Loading metrics

Open Access

Peer-reviewed

Research Article

Effects of MDM2, MDM4 and TP53 Codon 72 Polymorphisms on Cancer Risk in a Cohort Study of Carriers of TP53 Germline Mutations

Shenying Fang,

Affiliation Department of Epidemiology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Ralf Krahe,

Affiliation Department of Genetics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Guillermina Lozano,

Affiliation Department of Genetics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Younghun Han,

Affiliation Department of Epidemiology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Wei Chen,

Affiliation Department of Epidemiology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Sean M. Post,

Affiliation Department of Genetics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Baili Zhang,

Affiliation Department of Genetics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Charmaine D. Wilson,

Affiliation Department of Genetics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Linda L. Bachinski,

Affiliation Department of Genetics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Louise C. Strong ,

Contributed equally to this work with: Louise C. Strong, Christopher I. Amos

Affiliation Department of Genetics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Christopher I. Amos

Contributed equally to this work with: Louise C. Strong, Christopher I. Amos

* E-mail: camos@mdanderson.org

Affiliation Department of Epidemiology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯

Effects of MDM2, MDM4 and TP53 Codon 72 Polymorphisms on Cancer Risk in a Cohort Study of Carriers of TP53 Germline Mutations

Shenying Fang,
Ralf Krahe,
Guillermina Lozano,
Younghun Han,
Wei Chen,
Sean M. Post,
Baili Zhang,
Charmaine D. Wilson,
Linda L. Bachinski,
Louise C. Strong

Published: May 26, 2010
https://doi.org/10.1371/journal.pone.0010813

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Heredity
Is the Subject Area "Heredity" applicable to this article?

Thanks for your feedback.
Cancer risk factors
Is the Subject Area "Cancer risk factors" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Germline mutation
Is the Subject Area "Germline mutation" applicable to this article?

Thanks for your feedback.
Cancer detection and diagnosis
Is the Subject Area "Cancer detection and diagnosis" applicable to this article?

Thanks for your feedback.
Lung and intrathoracic tumors
Is the Subject Area "Lung and intrathoracic tumors" applicable to this article?

Thanks for your feedback.
Variant genotypes
Is the Subject Area "Variant genotypes" applicable to this article?

Thanks for your feedback.