Effective Melanoma Immunotherapy in Mice by the Skin-Depigmenting Agent Monobenzone and the Adjuvants Imiquimod and CpG

Jasper G. van den Boorn; Debby Konijnenberg; Esther P. M. Tjin; Daisy I. Picavet; Nico J. Meeuwenoord; Dmitri V. Filippov; J. P. Wietze van der Veen; Jan D. Bos; Cornelis J. M. Melief; Rosalie M. Luiten

doi:10.1371/journal.pone.0010626

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Open Access

Peer-reviewed

Research Article

Effective Melanoma Immunotherapy in Mice by the Skin-Depigmenting Agent Monobenzone and the Adjuvants Imiquimod and CpG

Jasper G. van den Boorn,

Affiliation Department of Dermatology and the Netherlands Institute for Pigment Disorders, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Debby Konijnenberg,

Affiliation Department of Dermatology and the Netherlands Institute for Pigment Disorders, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Esther P. M. Tjin,

Affiliation Department of Dermatology and the Netherlands Institute for Pigment Disorders, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Daisy I. Picavet,

Affiliation Department of Dermatology and the Netherlands Institute for Pigment Disorders, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Nico J. Meeuwenoord,

Affiliation Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands
⨯
Dmitri V. Filippov,

Affiliation Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands
⨯
J. P. Wietze van der Veen,

Affiliations Department of Dermatology and the Netherlands Institute for Pigment Disorders, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Dermatology, Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
⨯
Jan D. Bos,

Affiliation Department of Dermatology and the Netherlands Institute for Pigment Disorders, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Cornelis J. M. Melief,

Affiliation Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
⨯
Rosalie M. Luiten

* E-mail: r.m.luiten@amc.uva.nl

Affiliation Department of Dermatology and the Netherlands Institute for Pigment Disorders, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯

Effective Melanoma Immunotherapy in Mice by the Skin-Depigmenting Agent Monobenzone and the Adjuvants Imiquimod and CpG

Jasper G. van den Boorn,
Debby Konijnenberg,
Esther P. M. Tjin,
Daisy I. Picavet,
Nico J. Meeuwenoord,
Dmitri V. Filippov,
J. P. Wietze van der Veen,
Jan D. Bos,
Cornelis J. M. Melief,
Rosalie M. Luiten

Published: May 13, 2010
https://doi.org/10.1371/journal.pone.0010626

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