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Open Access

Peer-reviewed

Research Article

Capsaicin Displays Anti-Proliferative Activity against Human Small Cell Lung Cancer in Cell Culture and Nude Mice Models via the E2F Pathway

Kathleen C. Brown ,

Contributed equally to this work with: Kathleen C. Brown, Ted R. Witte

Affiliation Department of Pharmacology, Physiology and Toxicology, Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia, United States of America
⨯
Ted R. Witte ,

Contributed equally to this work with: Kathleen C. Brown, Ted R. Witte

Affiliation Department of Biochemistry and Microbiology, Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia, United States of America
⨯
W. Elaine Hardman,

Affiliation Department of Biochemistry and Microbiology, Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia, United States of America
⨯
Haitao Luo,

Affiliation Department of Biology, Alderson-Broaddus College, Phillipi, West Virginia, United States of America
⨯
Yi C. Chen,

Affiliation Department of Biology, Alderson-Broaddus College, Phillipi, West Virginia, United States of America
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A. Betts Carpenter,

Affiliation Department of Anatomy and Pathology, Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia, United States of America
⨯
Jamie K. Lau,

Affiliation Department of Pharmacology, Physiology and Toxicology, Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia, United States of America
⨯
Piyali Dasgupta

* E-mail: dasgupta@marshall.edu

Affiliation Department of Pharmacology, Physiology and Toxicology, Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia, United States of America
⨯

Capsaicin Displays Anti-Proliferative Activity against Human Small Cell Lung Cancer in Cell Culture and Nude Mice Models via the E2F Pathway

Kathleen C. Brown,
Ted R. Witte,
W. Elaine Hardman,
Haitao Luo,
Yi C. Chen,
A. Betts Carpenter,
Jamie K. Lau,
Piyali Dasgupta

x

Published: April 20, 2010
https://doi.org/10.1371/journal.pone.0010243

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Cyclins
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Synthesis phase
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