Homeodomain Interacting Protein Kinase 2: A Target for Alzheimer's Beta Amyloid Leading to Misfolded p53 and Inappropriate Cell Survival

Cristina Lanni; Lavinia Nardinocchi; Rosa Puca; Serena Stanga; Daniela Uberti; Maurizio Memo; Stefano Govoni; Gabriella D'Orazi; Marco Racchi

doi:10.1371/journal.pone.0010171

Loading metrics

Open Access

Peer-reviewed

Research Article

Homeodomain Interacting Protein Kinase 2: A Target for Alzheimer's Beta Amyloid Leading to Misfolded p53 and Inappropriate Cell Survival

Cristina Lanni ,

Contributed equally to this work with: Cristina Lanni, Lavinia Nardinocchi

* E-mail: cristina.lanni@unipv.it

Affiliation Department of Experimental and Applied Pharmacology, Centre of Excellence in Applied Biology, University of Pavia, Pavia, Italy
⨯
Lavinia Nardinocchi ,

Contributed equally to this work with: Cristina Lanni, Lavinia Nardinocchi

Affiliations Molecular Oncogenesis Laboratory, Department of Experimental Oncology, National Cancer Institute Regina Elena, Rome, Italy, Department of Oncology and Neurosciences, University “G. d'Annunzio”, Chieti, Italy
⨯
Rosa Puca,

Affiliations Molecular Oncogenesis Laboratory, Department of Experimental Oncology, National Cancer Institute Regina Elena, Rome, Italy, Department of Oncology and Neurosciences, University “G. d'Annunzio”, Chieti, Italy
⨯
Serena Stanga,

Affiliation Department of Experimental and Applied Pharmacology, Centre of Excellence in Applied Biology, University of Pavia, Pavia, Italy
⨯
Daniela Uberti,

Affiliation Department of Biomedical Sciences and Biotechnologies, University of Brescia, Brescia, Italy
⨯
Maurizio Memo,

Affiliation Department of Biomedical Sciences and Biotechnologies, University of Brescia, Brescia, Italy
⨯
Stefano Govoni,

Affiliation Department of Experimental and Applied Pharmacology, Centre of Excellence in Applied Biology, University of Pavia, Pavia, Italy
⨯
Gabriella D'Orazi,

Affiliations Molecular Oncogenesis Laboratory, Department of Experimental Oncology, National Cancer Institute Regina Elena, Rome, Italy, Department of Oncology and Neurosciences, University “G. d'Annunzio”, Chieti, Italy
⨯
Marco Racchi

Affiliation Department of Experimental and Applied Pharmacology, Centre of Excellence in Applied Biology, University of Pavia, Pavia, Italy
⨯

Homeodomain Interacting Protein Kinase 2: A Target for Alzheimer's Beta Amyloid Leading to Misfolded p53 and Inappropriate Cell Survival

Cristina Lanni,
Lavinia Nardinocchi,
Rosa Puca,
Serena Stanga,
Daniela Uberti,
Maurizio Memo,
Stefano Govoni,
Gabriella D'Orazi,
Marco Racchi

Published: April 14, 2010
https://doi.org/10.1371/journal.pone.0010171

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Alzheimer's disease
Is the Subject Area "Alzheimer's disease" applicable to this article?

Thanks for your feedback.
Immunoprecipitation
Is the Subject Area "Immunoprecipitation" applicable to this article?

Thanks for your feedback.
Fibroblasts
Is the Subject Area "Fibroblasts" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Cell binding
Is the Subject Area "Cell binding" applicable to this article?

Thanks for your feedback.
Zinc
Is the Subject Area "Zinc" applicable to this article?

Thanks for your feedback.
DNA-binding proteins
Is the Subject Area "DNA-binding proteins" applicable to this article?

Thanks for your feedback.