Hemolysis Is Associated with Low Reticulocyte Production Index and Predicts Blood Transfusion in Severe Malarial Anemia

Rolf Fendel; Christian Brandts; Annika Rudat; Andrea Kreidenweiss; Claudia Steur; Iris Appelmann; Bettina Ruehe; Paul Schröder; Wolfgang E. Berdel; Peter G. Kremsner; Benjamin Mordmüller

doi:10.1371/journal.pone.0010038

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Peer-reviewed

Research Article

Hemolysis Is Associated with Low Reticulocyte Production Index and Predicts Blood Transfusion in Severe Malarial Anemia

Rolf Fendel ,

Contributed equally to this work with: Rolf Fendel, Christian Brandts

Affiliations Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon, Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany, Department of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois, United States of America
⨯
Christian Brandts ,

Contributed equally to this work with: Rolf Fendel, Christian Brandts

Affiliations Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon, Department of Medicine, Hematology/Oncology, University of Münster, Münster, Germany, Department of Medicine, Hematology/Oncology, Goethe-University, Frankfurt, Germany
⨯
Annika Rudat,

Affiliations Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon, Department of Medicine, Hematology/Oncology, University of Münster, Münster, Germany
⨯
Andrea Kreidenweiss,

Affiliations Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon, Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany
⨯
Claudia Steur,

Affiliation Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon
⨯
Iris Appelmann,

Affiliations Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon, Department of Medicine, Hematology/Oncology, University of Münster, Münster, Germany
⨯
Bettina Ruehe,

Affiliation Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon
⨯
Paul Schröder,

Affiliation Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon
⨯
Wolfgang E. Berdel,

Affiliation Department of Medicine, Hematology/Oncology, University of Münster, Münster, Germany
⨯
Peter G. Kremsner,

Affiliations Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon, Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany
⨯
Benjamin Mordmüller

* E-mail: benjamin.mordmueller@uni-tuebingen.de

Affiliations Medical Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon, Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany
⨯

Hemolysis Is Associated with Low Reticulocyte Production Index and Predicts Blood Transfusion in Severe Malarial Anemia

Rolf Fendel,
Christian Brandts,
Annika Rudat,
Andrea Kreidenweiss,
Claudia Steur,
Iris Appelmann,
Bettina Ruehe,
Paul Schröder,
Wolfgang E. Berdel,
Peter G. Kremsner

Published: April 6, 2010
https://doi.org/10.1371/journal.pone.0010038

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Malaria
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Phagocytosis
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Blood transfusion
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Reticulocytes
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Red blood cells
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Malarial parasites
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