CXCR4 Mediated Chemotaxis Is Regulated by 5T4 Oncofetal Glycoprotein in Mouse Embryonic Cells

Thomas D. Southgate; Owen J. McGinn; Fernanda V. Castro; Andrzej J. Rutkowski; Mariam Al-Muftah; Georgi Marinov; Graeme J. Smethurst; David Shaw; Christopher M. Ward; Crispin J. Miller; Peter L. Stern

doi:10.1371/journal.pone.0009982

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Open Access

Peer-reviewed

Research Article

CXCR4 Mediated Chemotaxis Is Regulated by 5T4 Oncofetal Glycoprotein in Mouse Embryonic Cells

Thomas D. Southgate,

Affiliation Immunology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom
⨯
Owen J. McGinn,

Affiliation Immunology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom
⨯
Fernanda V. Castro,

Affiliation Immunology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom
⨯
Andrzej J. Rutkowski,

Affiliations Immunology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom, Applied Computational Biology and Bioinformatics Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom
⨯
Mariam Al-Muftah,

Affiliation Immunology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom
⨯
Georgi Marinov,

Affiliation Immunology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom
⨯
Graeme J. Smethurst,

Affiliations Immunology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom, Applied Computational Biology and Bioinformatics Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom
⨯
David Shaw,

Affiliation Immunology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom
⨯
Christopher M. Ward,

Affiliation Immunology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom
⨯
Crispin J. Miller,

Affiliation Applied Computational Biology and Bioinformatics Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom
⨯
Peter L. Stern

* E-mail: pstern@picr.man.ac.uk

Affiliation Immunology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom
⨯

CXCR4 Mediated Chemotaxis Is Regulated by 5T4 Oncofetal Glycoprotein in Mouse Embryonic Cells

Thomas D. Southgate,
Owen J. McGinn,
Fernanda V. Castro,
Andrzej J. Rutkowski,
Mariam Al-Muftah,
Georgi Marinov,
Graeme J. Smethurst,
David Shaw,
Christopher M. Ward,
Crispin J. Miller

Published: April 1, 2010
https://doi.org/10.1371/journal.pone.0009982

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Cell differentiation
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Chemotaxis
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Chemokines
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Enzyme-linked immunoassays
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Lung and intrathoracic tumors
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