Oral Activated Charcoal Prevents Experimental Cerebral Malaria in Mice and in a Randomized Controlled Clinical Trial in Man Did Not Interfere with the Pharmacokinetics of Parenteral Artesunate

• J. Brian de Souza ,

  Contributed equally to this work with: J. Brian de Souza, Uduak Okomo

  Affiliations Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom, Division of Infection and Immunity, Department of Immunology, University College London, London, United Kingdom

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• Uduak Okomo ,

  Contributed equally to this work with: J. Brian de Souza, Uduak Okomo

  Affiliation Medical Research Council Laboratories, Fajara, Banjul, The Gambia

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• Neal D. Alexander,

  Affiliation Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

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• Naveed Aziz,

  Affiliation The Technology Facility, Department of Biology, University of York, York, United Kingdom

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• Benjamin M. J. Owens,

  Affiliation Centre for Immunology and Infection, Hull York Medical School and Department of Biology, University of York, York, United Kingdom

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• Harparkash Kaur,

  Affiliation Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

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• Momodou Jasseh,

  Affiliation Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

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• Sant Muangnoicharoen,

  Affiliation Liverpool School of Tropical Medicine, Liverpool, United Kingdom

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• Percy F. Sumariwalla,

  Affiliation Kennedy Institute of Rheumatology, Imperial College of Science, London, United Kingdom

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• David C. Warhurst,

  Affiliation Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

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• Stephen A. Ward,

  Affiliation Liverpool School of Tropical Medicine, Liverpool, United Kingdom

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• David J. Conway,

  Affiliations Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom, Medical Research Council Laboratories, Fajara, Banjul, The Gambia

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• Luis Ulloa,

  Affiliation Center of Immunology and Inflammation, North Shore-LIJ Research Institute, New York, New York, United States of America

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• Kevin J. Tracey,

  Affiliation Center of Immunology and Inflammation, North Shore-LIJ Research Institute, New York, New York, United States of America

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• Brian M. J. Foxwell,

  Affiliation Kennedy Institute of Rheumatology, Imperial College of Science, London, United Kingdom

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• Paul M. Kaye ,

  * E-mail: pmk2@york.ac.uk (PMK); mwalther@mrc.gm (MW)

  Affiliation Centre for Immunology and Infection, Hull York Medical School and Department of Biology, University of York, York, United Kingdom

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•  [ ... ],
• Michael Walther

  * E-mail: pmk2@york.ac.uk (PMK); mwalther@mrc.gm (MW)

  Affiliation Medical Research Council Laboratories, Fajara, Banjul, The Gambia

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