Interaction of E2 Glycoprotein with Heparan Sulfate Is Crucial for Cellular Infection of Sindbis Virus

Wuyang Zhu; Lihua Wang; Yiliang Yang; Juan Jia; Shihong Fu; Yun Feng; Ying He; Jin-Ping Li; Guodong Liang

doi:10.1371/journal.pone.0009656

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Open Access

Peer-reviewed

Research Article

Interaction of E2 Glycoprotein with Heparan Sulfate Is Crucial for Cellular Infection of Sindbis Virus

Wuyang Zhu ,

Contributed equally to this work with: Wuyang Zhu, Lihua Wang

Affiliation Department of Viral Encephalitis, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (IVDC, China CDC) and State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Beijing, China
⨯
Lihua Wang ,

Contributed equally to this work with: Wuyang Zhu, Lihua Wang

Affiliation Department of Viral Encephalitis, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (IVDC, China CDC) and State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Beijing, China
⨯
Yiliang Yang,

Affiliation Department of Viral Encephalitis, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (IVDC, China CDC) and State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Beijing, China
⨯
Juan Jia,

Affiliation Department of Medical Biochemistry and Microbiology, University of Uppsala, Uppsala, Sweden
⨯
Shihong Fu,

Affiliation Department of Viral Encephalitis, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (IVDC, China CDC) and State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Beijing, China
⨯
Yun Feng,

Affiliation Department of Viral Encephalitis, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (IVDC, China CDC) and State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Beijing, China
⨯
Ying He,

Affiliation Department of Viral Encephalitis, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (IVDC, China CDC) and State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Beijing, China
⨯
Jin-Ping Li,

Affiliation Department of Medical Biochemistry and Microbiology, University of Uppsala, Uppsala, Sweden
⨯
Guodong Liang

* E-mail: gdliang@hotmail.com

Affiliation Department of Viral Encephalitis, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (IVDC, China CDC) and State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Beijing, China
⨯

Interaction of E2 Glycoprotein with Heparan Sulfate Is Crucial for Cellular Infection of Sindbis Virus

Wuyang Zhu,
Lihua Wang,
Yiliang Yang,
Juan Jia,
Shihong Fu,
Yun Feng,
Ying He,
Jin-Ping Li,
Guodong Liang

Published: March 11, 2010
https://doi.org/10.1371/journal.pone.0009656

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Heparin
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Sindbis virus
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E2 glycoproteins
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Protein interactions
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