Unique Biological Properties of Catalytic Domain Directed Human Anti-CAIX Antibodies Discovered through Phage-Display Technology

Chen Xu; Agnes Lo; Anuradha Yammanuru; Aimee St. Clair Tallarico; Kristen Brady; Akikazu Murakami; Natasha Barteneva; Quan Zhu; Wayne A. Marasco

doi:10.1371/journal.pone.0009625

Loading metrics

Open Access

Peer-reviewed

Research Article

Unique Biological Properties of Catalytic Domain Directed Human Anti-CAIX Antibodies Discovered through Phage-Display Technology

Chen Xu,

Current address: Beijing Tri-prime Genetic Engineering Corporation, Limited, Beijing, People's Republic of China

Affiliations Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Agnes Lo,

Affiliations Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Anuradha Yammanuru,

Affiliation Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Aimee St. Clair Tallarico,

Affiliation Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Kristen Brady,

Affiliation Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Akikazu Murakami,

Affiliation Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Natasha Barteneva,

Affiliations Immune Disease Institute and Program in Cellular and Molecular Medicine, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Quan Zhu ,

* E-mail: quan_zhu@dfci.harvard.edu (QZ); wayne_marasco@dfci.harvard.edu (WAM)

Affiliations Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Wayne A. Marasco

* E-mail: quan_zhu@dfci.harvard.edu (QZ); wayne_marasco@dfci.harvard.edu (WAM)

Affiliations Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Unique Biological Properties of Catalytic Domain Directed Human Anti-CAIX Antibodies Discovered through Phage-Display Technology

Chen Xu,
Agnes Lo,
Anuradha Yammanuru,
Aimee St. Clair Tallarico,
Kristen Brady,
Akikazu Murakami,
Natasha Barteneva,
Quan Zhu,
Wayne A. Marasco

Published: March 10, 2010
https://doi.org/10.1371/journal.pone.0009625

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.
Renal cell carcinoma
Is the Subject Area "Renal cell carcinoma" applicable to this article?

Thanks for your feedback.
Enzyme-linked immunoassays
Is the Subject Area "Enzyme-linked immunoassays" applicable to this article?

Thanks for your feedback.
Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Renal cancer
Is the Subject Area "Renal cancer" applicable to this article?

Thanks for your feedback.
Carbonic anhydrases
Is the Subject Area "Carbonic anhydrases" applicable to this article?

Thanks for your feedback.
Binding analysis
Is the Subject Area "Binding analysis" applicable to this article?

Thanks for your feedback.
Cell staining
Is the Subject Area "Cell staining" applicable to this article?

Thanks for your feedback.