Reactivation of Latent Tuberculosis in Cynomolgus Macaques Infected with SIV Is Associated with Early Peripheral T Cell Depletion and Not Virus Load

Collin R. Diedrich; Joshua T. Mattila; Edwin Klein; Chris Janssen; Jiayao Phuah; Timothy J. Sturgeon; Ronald C. Montelaro; Philana Ling Lin; JoAnne L. Flynn

doi:10.1371/journal.pone.0009611

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Peer-reviewed

Research Article

Reactivation of Latent Tuberculosis in Cynomolgus Macaques Infected with SIV Is Associated with Early Peripheral T Cell Depletion and Not Virus Load

Collin R. Diedrich ,

Contributed equally to this work with: Collin R. Diedrich, Joshua T. Mattila

Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Joshua T. Mattila ,

Contributed equally to this work with: Collin R. Diedrich, Joshua T. Mattila

Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Edwin Klein,

Affiliation Division of Laboratory Animal Resources, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Chris Janssen,

Affiliation Division of Laboratory Animal Resources, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Jiayao Phuah,

Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Timothy J. Sturgeon,

Affiliation Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Ronald C. Montelaro,

Affiliation Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Philana Ling Lin,

Affiliation Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
⨯
JoAnne L. Flynn

* E-mail: joanne@pitt.edu

Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯

Reactivation of Latent Tuberculosis in Cynomolgus Macaques Infected with SIV Is Associated with Early Peripheral T Cell Depletion and Not Virus Load

Collin R. Diedrich,
Joshua T. Mattila,
Edwin Klein,
Chris Janssen,
Jiayao Phuah,
Timothy J. Sturgeon,
Ronald C. Montelaro,
Philana Ling Lin,
JoAnne L. Flynn

Published: March 10, 2010
https://doi.org/10.1371/journal.pone.0009611

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11 Mar 2015
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Inoculation dose correction Posted by crd64 on 11 Mar 2015 at 17:24 GMT
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10 Mar 2010
16:25 GMT
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Author Summary Posted by CRD32 on 10 Mar 2010 at 16:25 GMT

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