A New Adenovirus Based Vaccine Vector Expressing an Eimeria tenella Derived TLR Agonist Improves Cellular Immune Responses to an Antigenic Target

Daniel M. Appledorn; Yasser A. Aldhamen; William DePas; Sergey S. Seregin; Chyong-Jy J. Liu; Nathan Schuldt; Darin Quach; Dionisia Quiroga; Sarah Godbehere; Igor Zlatkin; Sungjin Kim; J. Justin McCormick; Andrea Amalfitano

doi:10.1371/journal.pone.0009579

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Open Access

Peer-reviewed

Research Article

A New Adenovirus Based Vaccine Vector Expressing an Eimeria tenella Derived TLR Agonist Improves Cellular Immune Responses to an Antigenic Target

Daniel M. Appledorn,

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯
Yasser A. Aldhamen,

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯
William DePas,

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯
Sergey S. Seregin,

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯
Chyong-Jy J. Liu,

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯
Nathan Schuldt,

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯
Darin Quach,

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯
Dionisia Quiroga,

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯
Sarah Godbehere,

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯
Igor Zlatkin,

Affiliation Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, United States of America
⨯
Sungjin Kim,

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯
J. Justin McCormick,

Affiliations Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America, Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, United States of America
⨯
Andrea Amalfitano

* E-mail: amalfit1@msu.edu

Affiliation Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America
⨯

A New Adenovirus Based Vaccine Vector Expressing an Eimeria tenella Derived TLR Agonist Improves Cellular Immune Responses to an Antigenic Target

Daniel M. Appledorn,
Yasser A. Aldhamen,
William DePas,
Sergey S. Seregin,
Chyong-Jy J. Liu,
Nathan Schuldt,
Darin Quach,
Dionisia Quiroga,
Sarah Godbehere,
Igor Zlatkin

Published: March 8, 2010
https://doi.org/10.1371/journal.pone.0009579

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