The PPARβ/δAgonist GW0742 Relaxes Pulmonary Vessels and Limits Right Heart Hypertrophy in Rats with Hypoxia-Induced Pulmonary Hypertension

Open Access

Peer-reviewed

Research Article

Louise S. Harrington,

Affiliation Cardiothoracic Pharmacology, NHLI, Imperial College London, United Kingdom
⨯
Laura Moreno,

Affiliation Cardiothoracic Pharmacology, NHLI, Imperial College London, United Kingdom
⨯
Anna Reed,

Affiliation Cardiothoracic Pharmacology, NHLI, Imperial College London, United Kingdom
⨯
Stephen J. Wort,

Affiliation Critical Care Medicine, NHLI, Royal Brompton Hospital, London, United Kingdom
⨯
Béatrice Desvergne,

Affiliation Center for Integrative Genomics, University of Lausanne, Genopode, Lausanne, Switzerland
⨯
Christopher Garland,

Affiliation Department of Pharmacology, University of Oxford, Oxford, United Kingdom
⨯
Lan Zhao,

Affiliation Experimental Medicine and Toxicology, Hammersmith Hospital, Imperial College London, London, United Kingdom
⨯
Jane A. Mitchell

* E-mail: j.a.mitchell@ic.ac.uk

Affiliation Cardiothoracic Pharmacology, NHLI, Imperial College London, United Kingdom
⨯

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Pulmonary arteries
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Medical hypoxia
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Pulmonary hypertension
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Mesenteric arteries
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Aorta
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Blood vessels
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Prostacyclin
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Systolic pressure
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