Phylogenomic Analyses Reveal the Evolutionary Origin of the Inhibin α-Subunit, a Unique TGFβ Superfamily Antagonist

Jie Zhu; Edward L. Braun; Satomi Kohno; Monica Antenos; Eugene Y. Xu; Robert W. Cook; S. Jack Lin; Brandon C. Moore; Louis J. Guillette Jr; Theodore S. Jardetzky; Teresa K. Woodruff

doi:10.1371/journal.pone.0009457

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Peer-reviewed

Research Article

Phylogenomic Analyses Reveal the Evolutionary Origin of the Inhibin α-Subunit, a Unique TGFβ Superfamily Antagonist

Jie Zhu,

Affiliation Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
⨯
Edward L. Braun,

Affiliation Department of Biology, University of Florida, Gainesville, Florida, United States of America
⨯
Satomi Kohno,

Affiliation Department of Biology, University of Florida, Gainesville, Florida, United States of America
⨯
Monica Antenos,

Affiliation Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
⨯
Eugene Y. Xu,

Affiliation Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
⨯
Robert W. Cook,

Affiliation Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
⨯
S. Jack Lin,

Affiliation Department of Structural Biology, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Brandon C. Moore,

Affiliation Department of Biology, University of Florida, Gainesville, Florida, United States of America
⨯
Louis J. Guillette Jr,

Affiliation Department of Biology, University of Florida, Gainesville, Florida, United States of America
⨯
Theodore S. Jardetzky,

Affiliation Department of Structural Biology, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Teresa K. Woodruff

* E-mail: tkw@northwestern.edu

Affiliation Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
⨯

Phylogenomic Analyses Reveal the Evolutionary Origin of the Inhibin α-Subunit, a Unique TGFβ Superfamily Antagonist

Jie Zhu,
Edward L. Braun,
Satomi Kohno,
Monica Antenos,
Eugene Y. Xu,
Robert W. Cook,
S. Jack Lin,
Brandon C. Moore,
Louis J. Guillette Jr,
Theodore S. Jardetzky

Published: March 4, 2010
https://doi.org/10.1371/journal.pone.0009457

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