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Open Access
Peer-reviewed
Research Article
MYC Overexpression Induces Prostatic Intraepithelial Neoplasia and Loss of Nkx3.1 in Mouse Luminal Epithelial Cells
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Tsuyoshi Iwata,
Affiliation Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Denise Schultz,
Affiliation Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Jessica Hicks,
Affiliation Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Gretchen K. Hubbard,
Affiliation Department of Biological Sciences, The University of Maryland Baltimore County, Baltimore, Maryland, United States of America
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Laura N. Mutton,
Affiliation Department of Biological Sciences, The University of Maryland Baltimore County, Baltimore, Maryland, United States of America
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Tamara L. Lotan,
Affiliations Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Carlise Bethel,
Affiliations Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Matthew T. Lotz,
Affiliation Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Srinivasan Yegnasubramanian,
Affiliations Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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William G. Nelson,
Affiliations Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, The Brady Urological Research Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Chi V. Dang,
Affiliations Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Hematology and Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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MengMeng Xu,
Affiliation Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Uzoma Anele,
Affiliation Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Cheryl M. Koh,
Affiliation Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Charles J. Bieberich,
Affiliation Department of Biological Sciences, The University of Maryland Baltimore County, Baltimore, Maryland, United States of America
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Angelo M. De Marzo
* E-mail: ademarz@jhmi.edu
Affiliations Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, The Brady Urological Research Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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MYC Overexpression Induces Prostatic Intraepithelial Neoplasia and Loss of Nkx3.1 in Mouse Luminal Epithelial Cells
- Tsuyoshi Iwata,
- Denise Schultz,
- Jessica Hicks,
- Gretchen K. Hubbard,
- Laura N. Mutton,
- Tamara L. Lotan,
- Carlise Bethel,
- Matthew T. Lotz,
- Srinivasan Yegnasubramanian,
- William G. Nelson
- Published: February 25, 2010
- https://doi.org/10.1371/journal.pone.0009427